Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1983 1
1998 2
2000 1
2001 1
2003 1
2005 2
2006 2
2007 2
2008 2
2009 4
2010 3
2011 1
2012 7
2013 2
2014 2
2020 1
2021 3
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

36 results

Results by year

Filters applied: . Clear all
Page 1
Tolerability and Efficacy of Clindamycin/Tretinoin versus Adapalene/Benzoyl Peroxide in the Treatment of Acne Vulgaris.
Aschoff R, Möller S, Haase R, Kuske M. Aschoff R, et al. J Drugs Dermatol. 2021 Mar 1;20(3):295-301. doi: 10.36849/JDD.2021.5641. J Drugs Dermatol. 2021. PMID: 33683070 Clinical Trial.
This evaluator-blinded pilot study compared the efficacy and tolerability of two marketed topical combination acne gels, clindamycin 1%-tretinoin 0.025% (CT) and benzoyl peroxide 2.5%-adapalene 0.1% (BA) in 20 patients with mild to moderate acne vulgaris. ...
This evaluator-blinded pilot study compared the efficacy and tolerability of two marketed topical combination acne gels, clindamycin …
Clindamycin phosphate 1.2% and tretinoin 0.025% gel for rosacea: summary of a placebo-controlled, double-blind trial.
Freeman SA, Moon SD, Spencer JM. Freeman SA, et al. J Drugs Dermatol. 2012 Dec;11(12):1410-4. J Drugs Dermatol. 2012. PMID: 23377509 Clinical Trial.
Retinoids are not routinely indicated as treatment because of the common conception that they would be too inflammatory for the sensitive rosacea patient. However, photodamage may play a role in rosacea and tretinoin is well-known to repair photodamage. Thirty rosacea subj …
Retinoids are not routinely indicated as treatment because of the common conception that they would be too inflammatory for the sensitive ro …
Efficacy and tolerability of short contact therapy with tretinoin, clindamycin, and glycolic acid gel in acne: A randomized, controlled, assessor-blinded two-center trial: The MASCOTTE study.
Bertolani MB, Rodighiero E, Gandolfi M, Lotti T, Pedrazzi G, Puviani M, Milani M, Feliciani C, Satolli F. Bertolani MB, et al. Dermatol Ther. 2021 Jan;34(1):e14724. doi: 10.1111/dth.14724. Epub 2021 Jan 6. Dermatol Ther. 2021. PMID: 33377285 Clinical Trial.
A strategy to increase local tolerability is the "short contact therapy" (SCT) approach, consisting in the application of the product with the complete removal after 30 to 60 minutes using a non-aggressive cleanser. A gel containing tretinoin 0.02%, clindamycin 0.8% …
A strategy to increase local tolerability is the "short contact therapy" (SCT) approach, consisting in the application of the product with t …
Tolerability of clindamycin/tretinoin gel vs. tretinoin microsphere gel and adapalene gel.
Leyden J, Wortzman M, Baldwin EK. Leyden J, et al. J Drugs Dermatol. 2009 Apr;8(4):383-8. J Drugs Dermatol. 2009. PMID: 19363857 Clinical Trial.
BACKGROUND: Newer agents and formulations seek to improve the tolerability of topical retinoid therapy. Recently, a gel containing crystalline clindamycin 1.2% and tretinoin 0.025% (CLIN/RA) was approved by the U.S. ...Patients were randomized to either tretinoin …
BACKGROUND: Newer agents and formulations seek to improve the tolerability of topical retinoid therapy. Recently, a gel containing crystalli …
Efficacy and safety comparison of combination of 0.04% tretinoin microspheres plus 1% clindamycin versus their monotherapy in patients with acne vulgaris: a phase 3, randomized, double-blind study.
Dogra S, Sumathy TK, Nayak C, Ravichandran G, Vaidya PP, Mehta S, Mittal R, Mane A, Charugulla SN. Dogra S, et al. J Dermatolog Treat. 2021 Dec;32(8):925-933. doi: 10.1080/09546634.2020.1720579. Epub 2020 Feb 5. J Dermatolog Treat. 2021. PMID: 32020824 Clinical Trial.
The present study aimed to evaluate efficacy and safety of a novel tretinoin (microsphere, 0.04%) formulation in combination with clindamycin (1%) gel for treatment of acne vulgaris. MATERIALS AND METHODS: This phase 3 randomized, double-blind study included patient …
The present study aimed to evaluate efficacy and safety of a novel tretinoin (microsphere, 0.04%) formulation in combination with …
Transdermal absorption of clindamycin and tretinoin from topically applied anti-acne formulations in man.
van Hoogdalem EJ, Baven TL, Spiegel-Melsen I, Terpstra IJ. van Hoogdalem EJ, et al. Biopharm Drug Dispos. 1998 Dec;19(9):563-9. doi: 10.1002/(sici)1099-081x(199812)19:9<563::aid-bdd134>3.0.co;2-e. Biopharm Drug Dispos. 1998. PMID: 9872337 Clinical Trial.
Clindamycin urinary excretion for 12 h after application of the clindamycin phosphate/tretinoin gel was comparable to the values of the reference lotion, whereas the clindamycin HCl/tretinoin gel gave significantly higher values. ...In a separat …
Clindamycin urinary excretion for 12 h after application of the clindamycin phosphate/tretinoin gel was comparable to t …
Efficacy and safety of clindamycin-tretinoin gel versus clindamycin or tretinoin alone in acne vulgaris: a randomized, double-blind, vehicle-controlled study.
Jarratt MT, Brundage T. Jarratt MT, et al. J Drugs Dermatol. 2012 Mar;11(3):318-26. J Drugs Dermatol. 2012. PMID: 22395582 Clinical Trial.
METHODS: 1,649 participants were randomized 2:2:2:1 to 12 weeks of double-blind treatment with CT gel, clindamycin, tretinoin, or vehicle gel administered once daily. RESULTS: Significantly more participants achieved 2-grade or greater improvement on the Investigato …
METHODS: 1,649 participants were randomized 2:2:2:1 to 12 weeks of double-blind treatment with CT gel, clindamycin, tretinoin, …
Efficacy and safety of clindamycin phosphate 1.2%/tretinoin 0.025% formulation for the treatment of acne vulgaris: pooled analysis of data from three randomised, double-blind, parallel-group, phase III studies.
Dréno B, Bettoli V, Ochsendorf F, Layton AM, Perez M, Dakovic R, Gollnick H. Dréno B, et al. Eur J Dermatol. 2014 Mar-Apr;24(2):201-9. doi: 10.1684/ejd.2014.2293. Eur J Dermatol. 2014. PMID: 24704684 Clinical Trial.
BACKGROUND: The efficacy and safety of clindamycin phosphate 1.2%/tretinoin 0.025% (Clin-RA) were evaluated in three 12-week randomised studies. ...A greater proportion of Clin-RA treated patients had a 50% or 80% continuous reduction in all types of lesions at week …
BACKGROUND: The efficacy and safety of clindamycin phosphate 1.2%/tretinoin 0.025% (Clin-RA) were evaluated in three 12-week r …
The phototoxic and photoallergy potential of clindamycin phosphate 1.2%/ tretinoin 0.025% gel for facial acne: results of two single-center, evaluator-blinded, randomized, vehicle-controlled phase 1 studies in healthy volunteers.
Murray J, Potts A. Murray J, et al. J Drugs Dermatol. 2014 Jan;13(1):16-22. J Drugs Dermatol. 2014. PMID: 24385115 Clinical Trial.
BACKGROUND: A fixed-dose combination of clindamycin phosphate 1.2% and tretinoin 0.025% gel (VELTIN (clindamycin phosphate and tretinoin) 1.2%/0.025% Gel [VELTIN]) (clindamycin/tretinoin gel) is currently available for the once-daily topi …
BACKGROUND: A fixed-dose combination of clindamycin phosphate 1.2% and tretinoin 0.025% gel (VELTIN (clindamycin phosph …
In vivo antibacterial effects of tretinoin-clindamycin and clindamycin alone on Propionibacterium acnes with varying clindamycin minimum inhibitory.
Leyden JJ. Leyden JJ. J Drugs Dermatol. 2012 Dec;11(12):1434-8. J Drugs Dermatol. 2012. PMID: 23377513 Clinical Trial.
OBJECTIVE: To quantify the antimicrobial effect of clindamycin phosphate 1.2% and tretinoin 0.025% gel and 1% clindamycin phosphate gel in patients with Propionibacterium acnes of varying sensitivity to clindamycin. ...Use of clindamycin phospha …
OBJECTIVE: To quantify the antimicrobial effect of clindamycin phosphate 1.2% and tretinoin 0.025% gel and 1% clindamycin …
36 results