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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1973 1
1975 1
1976 1
1982 2
1984 4
1985 2
1986 3
1987 1
1988 6
1989 2
1990 3
1991 2
1993 4
1994 6
1995 7
1996 2
1997 4
1998 4
1999 6
2000 8
2001 4
2002 6
2003 9
2004 7
2005 4
2006 10
2007 6
2008 8
2009 9
2010 6
2011 7
2012 9
2013 8
2014 6
2015 5
2016 9
2017 9
2018 8
2019 9
2020 8
2021 7
2022 9
2023 3
2024 1

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212 results

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Page 1
Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance.
Suez J, Cohen Y, Valdés-Mas R, Mor U, Dori-Bachash M, Federici S, Zmora N, Leshem A, Heinemann M, Linevsky R, Zur M, Ben-Zeev Brik R, Bukimer A, Eliyahu-Miller S, Metz A, Fischbein R, Sharov O, Malitsky S, Itkin M, Stettner N, Harmelin A, Shapiro H, Stein-Thoeringer CK, Segal E, Elinav E. Suez J, et al. Cell. 2022 Sep 1;185(18):3307-3328.e19. doi: 10.1016/j.cell.2022.07.016. Epub 2022 Aug 19. Cell. 2022. PMID: 35987213 Free article. Clinical Trial.
We causally assessed NNS impacts in humans and their microbiomes in a randomized-controlled trial encompassing 120 healthy adults, administered saccharin, sucralose, aspartame, and stevia sachets for 2 weeks in doses lower than the acceptable daily intake, compared with co …
We causally assessed NNS impacts in humans and their microbiomes in a randomized-controlled trial encompassing 120 healthy adults, administe …
A randomized controlled trial contrasting the effects of 4 low-calorie sweeteners and sucrose on body weight in adults with overweight or obesity.
Higgins KA, Mattes RD. Higgins KA, et al. Am J Clin Nutr. 2019 May 1;109(5):1288-1301. doi: 10.1093/ajcn/nqy381. Am J Clin Nutr. 2019. PMID: 30997499 Free article. Clinical Trial.
Energy intake decreased with sucralose consumption (P = 0.02) and ingestive frequency was lower for sucralose than for saccharin (P = 0.045). Glucose tolerance was not significantly affected by any of the sweetener treatments. CONCLUSIONS: Sucrose and saccharin cons …
Energy intake decreased with sucralose consumption (P = 0.02) and ingestive frequency was lower for sucralose than for saccharin (P = …
High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice.
Serrano J, Smith KR, Crouch AL, Sharma V, Yi F, Vargova V, LaMoia TE, Dupont LM, Serna V, Tang F, Gomes-Dias L, Blakeslee JJ, Hatzakis E, Peterson SN, Anderson M, Pratley RE, Kyriazis GA. Serrano J, et al. Microbiome. 2021 Jan 12;9(1):11. doi: 10.1186/s40168-020-00976-w. Microbiome. 2021. PMID: 33431052 Free PMC article. Clinical Trial.
RESULTS: We conducted a double-blind, placebo-controlled, parallel arm study exploring the effects of pure saccharin compound on gut microbiota and glucose tolerance in healthy men and women. Participants were randomized to placebo, saccharin, lactisole (STR inhibit …
RESULTS: We conducted a double-blind, placebo-controlled, parallel arm study exploring the effects of pure saccharin compound on gut …
Effect of saccharin, a non-nutritive sweeteners, on insulin and blood glucose levels in healthy young men: A crossover trial.
Bayındır Gümüş A, Keser A, Tunçer E, Altuntaş Yıldız T, Kepenekci Bayram İ. Bayındır Gümüş A, et al. Diabetes Metab Syndr. 2022 Jun;16(6):102500. doi: 10.1016/j.dsx.2022.102500. Epub 2022 May 13. Diabetes Metab Syndr. 2022. PMID: 35598544 Clinical Trial.
The hypothesis of the study was there is an association between acute saccharin consumption and both glycemia and insulin response in young healthy adult men. ...CONCLUSIONS: Consequently, it was determined that saccharin had no glycemic effect. However, for the eff …
The hypothesis of the study was there is an association between acute saccharin consumption and both glycemia and insulin response in …
Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial.
Sáez-Alcaide LM, Molinero-Mourelle P, González-Serrano J, Rubio-Alonso L, Bornstein MM, López-Quiles J. Sáez-Alcaide LM, et al. Med Oral Patol Oral Cir Bucal. 2020 Sep 1;25(5):e644-e651. doi: 10.4317/medoral.23661. Med Oral Patol Oral Cir Bucal. 2020. PMID: 32683390 Free PMC article. Clinical Trial.
MATERIAL AND METHODS: A gel combining 0.2% chlorhexdine, 0.5% chitosan, 5% dexpanthenol, 0.15% allantoin and 0.01% sodium saccharin was selected for this split mouth randomized controlled and double-blind trial including 36 patients with bilaterally and symmetrically impac …
MATERIAL AND METHODS: A gel combining 0.2% chlorhexdine, 0.5% chitosan, 5% dexpanthenol, 0.15% allantoin and 0.01% sodium saccharin w …
Effects of rapid maxillary expansion or alternating rapid maxillary expansion and constriction on nasal mucociliary clearance : A randomized clinical trial.
Çoban Büyükbayraktar Z, Doruk C, Doğan M, Ertaş G. Çoban Büyükbayraktar Z, et al. J Orofac Orthop. 2022 Nov;83(6):395-402. doi: 10.1007/s00056-021-00316-z. Epub 2021 Jun 30. J Orofac Orthop. 2022. PMID: 34191034 Clinical Trial. English.
Patients were randomly distributed into two groups (n = 18 each)-one group was treated with the RME protocol and the other group was treated with the Alt-RAMEC protocol. MCC was evaluated using the saccharine transit time (STT) test, which was measured for each individual …
Patients were randomly distributed into two groups (n = 18 each)-one group was treated with the RME protocol and the other group was treated …
Non-Nutritive Sweeteners in Human Amniotic Fluid and Cord Blood: Evidence of Transplacental Fetal Exposure.
Halasa BC, Sylvetsky AC, Conway EM, Shouppe EL, Walter MF, Walter PJ, Cai H, Hui L, Rother KI. Halasa BC, et al. Am J Perinatol. 2023 Sep;40(12):1286-1291. doi: 10.1055/s-0041-1735555. Epub 2021 Sep 9. Am J Perinatol. 2023. PMID: 34500483 Clinical Trial.
RESULTS: Ten of 13 amniotic fluid samples contained at least one NNS (ace-K, saccharin, steviol glucuronide, and/or sucralose). Maximum amniotic fluid NNS concentrations of ace-K, saccharin, steviol glucuronide, and sucralose were 78.9, 55.9, 93.5, and 30.6 ng/mL, r …
RESULTS: Ten of 13 amniotic fluid samples contained at least one NNS (ace-K, saccharin, steviol glucuronide, and/or sucralose). Maxim …
Phototherapy for chronic rhinosinusitis.
Krespi YP, Kizhner V. Krespi YP, et al. Lasers Surg Med. 2011 Mar;43(3):187-91. doi: 10.1002/lsm.21042. Epub 2011 Feb 2. Lasers Surg Med. 2011. PMID: 21290392 Clinical Trial.
SNOT20 scores, NES, and cultures were obtained prior to illumination. Saccharin test was performed 1 week following treatment. RESULTS: Some cultures remained positive through treatment, with Staph. aureus predominating. ...No significant difference was observed between tw …
SNOT20 scores, NES, and cultures were obtained prior to illumination. Saccharin test was performed 1 week following treatment. RESULT …
New wand coblation turbinator vs coblation radiofrequency.
Islamoglu Y, Kesici GG, Bulut KS, Ozer EA, Canan Teleke Y, Babademez MA. Islamoglu Y, et al. Am J Otolaryngol. 2019 Sep-Oct;40(5):650-652. doi: 10.1016/j.amjoto.2019.05.019. Epub 2019 May 21. Am J Otolaryngol. 2019. PMID: 31130268 Clinical Trial.

(p < 0.001) There was no difference in pre-and-post operatively saccharin test results in CR group. (p = 0.385) There was slightly nasal flow gain in SCT group but this was not statistically significant. (p < 0.192) Also there was no statistically significant changes

…

(p < 0.001) There was no difference in pre-and-post operatively saccharin test results in CR group. (p = 0.385) There was slightly

…
Effects of sugammadex and neostigmine on mucociliary clearance in general anesthesia.
Ozciftci S, Sahiner Y, Sahiner IT. Ozciftci S, et al. Eur Rev Med Pharmacol Sci. 2022 Jun;26(12):4289-4294. doi: 10.26355/eurrev_202206_29067. Eur Rev Med Pharmacol Sci. 2022. PMID: 35776029 Free article. Clinical Trial.
PATIENTS AND METHODS: This prospective, randomized and double-blind study was performed on 60 non-smokers with ASA I-III underwent inguinal hernia repair under general anesthesia. Mucociliary clearance was assessed by nasal saccharine transit time (STT). After the preopera …
PATIENTS AND METHODS: This prospective, randomized and double-blind study was performed on 60 non-smokers with ASA I-III underwent inguinal …
212 results