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2005 2
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2008 4
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67 results

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Page 1
Examination of the "susceptibility gap" in the treatment of canine heartworm infection.
Bowman DD, Drake J. Bowman DD, et al. Parasit Vectors. 2017 Nov 9;10(Suppl 2):513. doi: 10.1186/s13071-017-2433-9. Parasit Vectors. 2017. PMID: 29143689 Free PMC article. Review.
A single intramuscular injection of 2.5 mg melarsomine dihydrochloride/kg has an efficacy of 82.1% against 4-month-old worms. ...Thiacetarsamide has been shown to be 99.7% effective against 2-month-old heartworms and other work has shown that melarsomine dihydrochlo …
A single intramuscular injection of 2.5 mg melarsomine dihydrochloride/kg has an efficacy of 82.1% against 4-month-old worms. ...Thia …
Heartworm adulticide treatment: a tropical perspective.
Dantas-Torres F, Ketzis J, Pérez Tort G, Mihalca AD, Baneth G, Otranto D, Watanabe M, Linh BK, Inpankaew T, Borrás P, Arumugam S, Penzhorn BL, Ybañez AP, Irwin P, Traub RJ. Dantas-Torres F, et al. Parasit Vectors. 2023 Apr 28;16(1):148. doi: 10.1186/s13071-023-05690-8. Parasit Vectors. 2023. PMID: 37106364 Free PMC article. Review.
In addition to the suitable climatic conditions that favour mosquito abundance and filarial larva development, there is low compliance with the recommended year-round use of preventives in these transmission hotspots. This represents a major concern, considering that melarsomi …
In addition to the suitable climatic conditions that favour mosquito abundance and filarial larva development, there is low compliance with …
Melarsomine suppresses canine osteosarcoma cell survival via inhibition of Hedgehog-GLI signaling.
Nam A, Kim T, Li Q, Rebhun RB, Youn HY, Seo KW. Nam A, et al. J Vet Med Sci. 2019 Dec 18;81(12):1722-1729. doi: 10.1292/jvms.19-0043. Epub 2019 Oct 22. J Vet Med Sci. 2019. PMID: 31645504 Free PMC article.
Cell viability and colony formation were decreased in the canine OSA cell lines Abrams and D17 after treatment with melarsomine. Melarsomine-induced apoptotic cell death was assessed via cell cycle analysis using propidium iodide staining. ...Additional studies are …
Cell viability and colony formation were decreased in the canine OSA cell lines Abrams and D17 after treatment with melarsomine. M …
Ultrasonography of the paralumbar muscles as a new aid during melarsomine treatment in canine heartworm disease. Description and illustration of the method - A preliminary study.
Vörös K, Becker Z, Dudás Györki Z, Schulze Gronover B, Szalay F. Vörös K, et al. Acta Vet Hung. 2022 Nov 17;70(4):263-268. doi: 10.1556/004.2022.00034. Print 2022 Dec 15. Acta Vet Hung. 2022. PMID: 36422692
Melarsomine is used intramuscularly to destroy adult heartworms when treating canine heartworm disease (HWD). ...Melarsomine was not fully gravitating, but its majority was spreading along the thickest fascia of the musculature. ...
Melarsomine is used intramuscularly to destroy adult heartworms when treating canine heartworm disease (HWD). ...Melarsomine w …
New paradigms in research on Dirofilaria immitis.
Geary TG. Geary TG. Parasit Vectors. 2023 Jul 21;16(1):247. doi: 10.1186/s13071-023-05762-9. Parasit Vectors. 2023. PMID: 37480077 Free PMC article. Review.
Since the advent of ivermectin (along with melarsomine and doxycycline), heartworm has come to be viewed as a solved problem in veterinary medicine, diminishing investment into non-clinical research on Dirofilaria immitis. ...
Since the advent of ivermectin (along with melarsomine and doxycycline), heartworm has come to be viewed as a solved problem in veter …
Treatment of dogs with severe heartworm disease.
Ames MK, Atkins CE. Ames MK, et al. Vet Parasitol. 2020 Jul;283:109131. doi: 10.1016/j.vetpar.2020.109131. Epub 2020 May 21. Vet Parasitol. 2020. PMID: 32521392 Review.
Acute hypersensitivity reactions after initiation of macrocyclic lactone preventive therapy in microfilaremic dogs or after melarsomine injection during adulticide therapy do occur, but are uncommon. ...
Acute hypersensitivity reactions after initiation of macrocyclic lactone preventive therapy in microfilaremic dogs or after melarsomine …
Application of Moxidectin and Ultrasound-Aided Injection of Melarsomine During the American Heartworm Society Recommended Treatment Protocol in Dirofilaria immitis Infected Dogs.
Vörös K, Becker Z, Kónya R, Arany-Tóth A, Farkas R. Vörös K, et al. Vector Borne Zoonotic Dis. 2022 Jul;22(7):382-390. doi: 10.1089/vbz.2021.0108. Epub 2022 Jun 10. Vector Borne Zoonotic Dis. 2022. PMID: 35687421
The American Heartworm Society (AHS) recommends the three-dose alternate melarsomine therapeutic regimen, together with a macrocyclic lactone (ML) to reduce new infections and eliminate susceptible larvae and doxycycline against Wolbachia bacteria. ...Transient anor …
The American Heartworm Society (AHS) recommends the three-dose alternate melarsomine therapeutic regimen, together with a macr …
Clinical benefits of incorporating doxycycline into a canine heartworm treatment protocol.
Nelson CT, Myrick ES, Nelson TA. Nelson CT, et al. Parasit Vectors. 2017 Nov 9;10(Suppl 2):515. doi: 10.1186/s13071-017-2446-4. Parasit Vectors. 2017. PMID: 29143657 Free PMC article.
These studies have shown a decrease in gross and microscopic pathology of pulmonary parenchyma in experimental heartworm infections pretreated with doxycycline before melarsomine administration. METHODS: Electronic medical records from a large veterinary practice in northe …
These studies have shown a decrease in gross and microscopic pathology of pulmonary parenchyma in experimental heartworm infections pretreat …
Thiacetarsamide (adulticide) versus melarsomine (RM 340) developed as macrofilaricide (adulticide and larvicide) to cure canine heartworm infection in dogs.
Raynaud JP. Raynaud JP. Ann Rech Vet. 1992;23(1):1-25. Ann Rech Vet. 1992. PMID: 1510336 Review.
After preliminary toxicity and efficacy models on experimentally infected dogs, in addition, to the reference posology (2.5 mg of melarsomine (RM 340)/kg twice, 24 h apart by deep IM injection) a more practical program for vet practitioners was suggested (2.2 mg/kg twice, …
After preliminary toxicity and efficacy models on experimentally infected dogs, in addition, to the reference posology (2.5 mg of melarso …
An evaluation of melarsomine hydrochloride efficacy for parasitological cure in experimental infection of dairy cattle with Trypanosoma evansi in Thailand.
Desquesnes M, Kamyingkird K, Vergne T, Sarataphan N, Pranee R, Jittapalapong S. Desquesnes M, et al. Parasitology. 2011 Aug;138(9):1134-42. doi: 10.1017/S0031182011000771. Epub 2011 Jul 18. Parasitology. 2011. PMID: 21767438
Melarsomine hydrochloride can cure Trypanosoma evansi infection in camels at a dose of 0.25 mg/kg, but at that dose relapses occur in cattle. ...It was concluded that the parasites had been cleared from the cattle, and melarsomine hydrochloride at 0.5 mg/kg can be r …
Melarsomine hydrochloride can cure Trypanosoma evansi infection in camels at a dose of 0.25 mg/kg, but at that dose relapses occur in …
67 results