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Year Number of Results
1999 1
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2008 1
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2023 2
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Page 1
The Adult Calfactant in Acute Respiratory Distress Syndrome Trial.
Willson DF, Truwit JD, Conaway MR, Traul CS, Egan EE. Willson DF, et al. Chest. 2015 Aug;148(2):356-364. doi: 10.1378/chest.14-1139. Chest. 2015. PMID: 25855884 Clinical Trial.
There were no significant baseline differences between groups. Calfactant administration was not associated with improved survival, lengths of stay, or oxygenation. Calfactant instillation was frequently associated with transient hypoxia and hypotension. ...
There were no significant baseline differences between groups. Calfactant administration was not associated with improved survival, l …
CALIPSO: A Randomized Controlled Trial of Calfactant for Acute Lung Injury in Pediatric Stem Cell and Oncology Patients.
Thomas NJ, Spear D, Wasserman E, Pon S, Markovitz B, Singh AR, Li S, Gertz SJ, Rowan CM, Kunselman A, Tamburro RF; CALIPSO Study Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators Network. Thomas NJ, et al. Biol Blood Marrow Transplant. 2018 Dec;24(12):2479-2486. doi: 10.1016/j.bbmt.2018.07.023. Epub 2018 Jul 29. Biol Blood Marrow Transplant. 2018. PMID: 30059785 Free PMC article. Clinical Trial.
Interventions used were intratracheal instillation of either calfactant or air placebo (1 or 2 doses). Forty-three subjects were enrolled between November 2010 and June 2015: 26 assigned to calfactant and 17 to placebo. ...Despite the risk-stratified randomization, …
Interventions used were intratracheal instillation of either calfactant or air placebo (1 or 2 doses). Forty-three subjects were enro …
Aerosolized Calfactant for Newborns With Respiratory Distress: A Randomized Trial.
Cummings JJ, Gerday E, Minton S, Katheria A, Albert G, Flores-Torres J, Famuyide M, Lampland A, Guthrie S, Kuehn D, Weitkamp JH, Fort P, Abu Jawdeh EG, Ryan RM, Martin GC, Swanson JR, Mulrooney N, Eyal F, Gerstmann D, Kumar P, Wilding GE, Egan EA; AERO-02 STUDY INVESTIGATORS. Cummings JJ, et al. Pediatrics. 2020 Nov;146(5):e20193967. doi: 10.1542/peds.2019-3967. Epub 2020 Oct 15. Pediatrics. 2020. PMID: 33060258 Clinical Trial.
METHODS: A prospective, multicenter, randomized, unblinded comparison trial of aerosolized calfactant (Infasurf) in newborns with signs of RDS that required noninvasive respiratory support. Calfactant was aerosolized by using a Solarys nebulizer modified with a paci …
METHODS: A prospective, multicenter, randomized, unblinded comparison trial of aerosolized calfactant (Infasurf) in newborns with sig …
Comparison of Infasurf (calfactant) and Survanta (beractant) in the prevention and treatment of respiratory distress syndrome.
Bloom BT, Clark RH; Infasurf Survanta Clinical Trial Group. Bloom BT, et al. Pediatrics. 2005 Aug;116(2):392-9. doi: 10.1542/peds.2004-2783. Pediatrics. 2005. PMID: 16061594 Clinical Trial.
METHODS: We performed 2 prospective, randomized, masked clinical trials; 1 trial used a prophylactic strategy aimed at prevention of respiratory distress syndrome (prophylaxis trial) for infants who were born between 23 weeks, 0 days and 29 weeks, 6 days of gestation, and the sec …
METHODS: We performed 2 prospective, randomized, masked clinical trials; 1 trial used a prophylactic strategy aimed at prevention of respira …
Post hoc analysis of calfactant use in immunocompromised children with acute lung injury: Impact and feasibility of further clinical trials.
Tamburro RF, Thomas NJ, Pon S, Jacobs BR, Dicarlo JV, Markovitz BP, Jefferson LS, Willson DF; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Tamburro RF, et al. Pediatr Crit Care Med. 2008 Sep;9(5):459-64. doi: 10.1097/PCC.0b013e3181849bec. Pediatr Crit Care Med. 2008. PMID: 18679142 Clinical Trial.
OBJECTIVE: To assess the impact of calfactant (a modified natural bovine lung surfactant) in immunocompromised children with acute lung injury and to determine the number of patients required for a definitive clinical trial of calfactant in this population. ...Ca …
OBJECTIVE: To assess the impact of calfactant (a modified natural bovine lung surfactant) in immunocompromised children with acute lu …
Anti-Inflammatory Effect of Surfactant Lipid in the Vaginal Mucosa: A Pilot Study.
MacNeill C, de Guzman GS, Lupo K, Umstead T, Phelps DS, Floros J. MacNeill C, et al. J Low Genit Tract Dis. 2019 Jan;23(1):71-74. doi: 10.1097/LGT.0000000000000448. J Low Genit Tract Dis. 2019. PMID: 30489432 Clinical Trial.
MATERIALS AND METHODS: Three groups of healthy cycling women were randomized to receive vaginally a single dose of the following: (1) low-dose calfactant, a type of surfactant lipids, 0.8 mg/ml; (2) high-dose calfactant 8.0 mg/ml; or (3) placebo, at the time of reso …
MATERIALS AND METHODS: Three groups of healthy cycling women were randomized to receive vaginally a single dose of the following: (1) low-do …
Response to aerosolized calfactant in infants with respiratory distress syndrome; a post-hoc analysis of AERO-02 trial.
Kaluarachchi DC, Zapata HA, Becker HL, Lasarev MR, Fort P, Guthrie SO. Kaluarachchi DC, et al. J Perinatol. 2023 Aug;43(8):998-1003. doi: 10.1038/s41372-023-01717-1. Epub 2023 Jul 10. J Perinatol. 2023. PMID: 37429958 Clinical Trial.
BACKGROUND: The aerosolized calfactant decreased the need for intubation in neonates with respiratory distress syndrome (AERO-02 trial). OBJECTIVE: To determine the oxygenation response to aerosolized calfactant among infants born 28 0/7-36 6/7 weeks with RDS in the …
BACKGROUND: The aerosolized calfactant decreased the need for intubation in neonates with respiratory distress syndrome (AERO-02 tria …
Imaging the postdeposition dispersion of an inhaled surfactant aerosol.
Corcoran TE, Thomas KM, Garoff S, Tilton RD, Przybycien TM, Pilewski JM. Corcoran TE, et al. J Aerosol Med Pulm Drug Deliv. 2012 Oct;25(5):290-6. doi: 10.1089/jamp.2011.0920. Epub 2012 Mar 6. J Aerosol Med Pulm Drug Deliv. 2012. PMID: 22393908 Free PMC article. Clinical Trial.
Peripheral lung activity decreased more rapidly on average with calfactant though the difference versus saline was not statistically significant. Central to peripheral count ratio decreased with saline and increased with calfactant and c/p changes approached signifi …
Peripheral lung activity decreased more rapidly on average with calfactant though the difference versus saline was not statistically …
Predictors of successful treatment of respiratory distress with aerosolized calfactant.
Hojnicki M, Zapata HA, Kaluarachchi DC, Fort P, Minton S, Albert G, Ross A, Wilding GE, Guthrie SO. Hojnicki M, et al. J Perinatol. 2023 Aug;43(8):991-997. doi: 10.1038/s41372-023-01722-4. Epub 2023 Jul 11. J Perinatol. 2023. PMID: 37433969 Clinical Trial.
METHODS: Neonates receiving nasal continuous positive airway pressure (NCPAP) at the time of first aerosolized calfactant administration were included in this analysis. Associations between demographic and clinical predictors to need for intubation were examined using univ …
METHODS: Neonates receiving nasal continuous positive airway pressure (NCPAP) at the time of first aerosolized calfactant administrat …
The relationship of fluid administration to outcome in the pediatric calfactant in acute respiratory distress syndrome trial.
Willson DF, Thomas NJ, Tamburro R, Truemper E, Truwit J, Conaway M, Traul C, Egan EE; Pediatric Acute Lung and Sepsis Investigators Network. Willson DF, et al. Pediatr Crit Care Med. 2013 Sep;14(7):666-72. doi: 10.1097/PCC.0b013e3182917cb5. Pediatr Crit Care Med. 2013. PMID: 23925143 Clinical Trial.
DESIGN: Calfactant in Acute Respiratory Distress Syndrome was a masked randomized controlled trial of calfactant surfactant versus placebo in pediatric patients with acute lung injury/acute respiratory distress syndrome due to direct lung injury. ...INTERVENTION: Po …
DESIGN: Calfactant in Acute Respiratory Distress Syndrome was a masked randomized controlled trial of calfactant surfactant ve …
21 results