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Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.
Matta MK, Florian J, Zusterzeel R, Pilli NR, Patel V, Volpe DA, Yang Y, Oh L, Bashaw E, Zineh I, Sanabria C, Kemp S, Godfrey A, Adah S, Coelho S, Wang J, Furlong LA, Ganley C, Michele T, Strauss DG. Matta MK, et al. JAMA. 2020 Jan 21;323(3):256-267. doi: 10.1001/jama.2019.20747. JAMA. 2020. PMID: 31961417 Free PMC article. Clinical Trial.
OBJECTIVE: To assess the systemic absorption and pharmacokinetics of the 6 active ingredients (avobenzone, oxybenzone, octocrylene, homosalate, octisalate, and octinoxate) in 4 sunscreen products under single- and maximal-use conditions. ...MAIN OUTCOM …
OBJECTIVE: To assess the systemic absorption and pharmacokinetics of the 6 active ingredients (avobenzone, oxybenzone, octocry …
In Vitro Testing of Sunscreens for Dermal Absorption: Method Comparison and Rank Order Correlation with In Vivo Absorption.
Yang Y, Ako-Adounvo AM, Wang J, Coelho SG, Adah SA, Matta MK, Strauss D, Michele TM, Wang J, Faustino PJ, O'Connor T, Ashraf M. Yang Y, et al. AAPS PharmSciTech. 2022 Apr 22;23(5):121. doi: 10.1208/s12249-022-02275-z. AAPS PharmSciTech. 2022. PMID: 35459978
The IVPT was used to evaluate dermal absorption of six UV filters (avobenzone, homosalate, octinoxate, octisalate, octocrylene, and oxybenzone) in commercial sunscreens. ...Rank orders of the cumulative in vitro skin permeation and the in vivo AUC were …
The IVPT was used to evaluate dermal absorption of six UV filters (avobenzone, homosalate, octinoxate, octisalate, octo …
Mechanistic Skin Modeling of Plasma Concentrations of Sunscreen Active Ingredients Following Facial Application.
Hamadeh A, Nash JF, Bialk H, Styczynski P, Troutman J, Edginton A. Hamadeh A, et al. J Pharm Sci. 2024 Mar;113(3):806-825. doi: 10.1016/j.xphs.2023.09.017. Epub 2023 Sep 26. J Pharm Sci. 2024. PMID: 37769994 Free article.
Building on earlier methods for predicting dermal disposition, a mechanistic model was developed to simulate plasma concentrations of seven organic sunscreen active ingredients: avobenzone, ensulizole, homosalate, octinoxate, octisalate, octocrylene, and o …
Building on earlier methods for predicting dermal disposition, a mechanistic model was developed to simulate plasma concentrations of seven …
Comparison between endocrine activity assessed using ToxCast/Tox21 database and human plasma concentration of sunscreen active ingredients/UV filters.
Onyango DO, Selman BG, Rose JL, Ellison CA, Nash JF. Onyango DO, et al. Toxicol Sci. 2023 Oct 30;196(1):25-37. doi: 10.1093/toxsci/kfad082. Toxicol Sci. 2023. PMID: 37561120 Free PMC article.
The ToxCast/Tox21 program, that is, CompTox, is a high-throughput in vitro screening database of chemicals that identify adverse outcome pathways, key events, and ED potential of chemicals. Using the ToxCast/Tox21 database, octisalate, homosalate, octocrylene, oxybenzon …
The ToxCast/Tox21 program, that is, CompTox, is a high-throughput in vitro screening database of chemicals that identify adverse outcome pat …