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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1980 1
1981 1
1985 1
1986 1
1987 1
1988 1
1992 1
1993 2
1994 1
1996 1
1997 2
1998 1
1999 2
2000 4
2001 2
2002 8
2003 4
2004 6
2005 10
2006 9
2007 7
2008 5
2009 14
2010 9
2011 6
2012 7
2013 7
2014 9
2015 12
2016 13
2017 11
2018 10
2019 9
2020 12
2021 18
2022 12
2023 8
2024 1

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211 results

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Page 1
Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Randomized Clinical Trial.
Krebs EE, Gravely A, Nugent S, Jensen AC, DeRonne B, Goldsmith ES, Kroenke K, Bair MJ, Noorbaloochi S. Krebs EE, et al. JAMA. 2018 Mar 6;319(9):872-882. doi: 10.1001/jama.2018.0899. JAMA. 2018. PMID: 29509867 Free PMC article. Clinical Trial.
In the opioid group, the first step was immediate-release morphine, oxycodone, or hydrocodone/acetaminophen. For the nonopioid group, the first step was acetaminophen (paracetamol) or a nonsteroidal anti-inflammatory drug. ...
In the opioid group, the first step was immediate-release morphine, oxycodone, or hydrocodone/acetaminophen. For the nonopioid …
Effectiveness of Oxycodone Hydrochloride (Strong Opioid) vs Combination Acetaminophen and Codeine (Mild Opioid) for Subacute Pain After Fractures Managed Surgically: A Randomized Clinical Trial.
Jenkin DE, Naylor JM, Descallar J, Harris IA. Jenkin DE, et al. JAMA Netw Open. 2021 Nov 1;4(11):e2134988. doi: 10.1001/jamanetworkopen.2021.34988. JAMA Netw Open. 2021. PMID: 34787656 Free PMC article. Clinical Trial.
Data were analyzed from June through October 2018. INTERVENTIONS: Initiation at discharge of oxycodone hydrochloride 5 mg of 10 mg (ie, 1 or 2 tablets) or combination acetaminophen and codeine 500 mg and 8 mg or 1000 mg and 16 mg (ie, 1 or 2 tablets) 4 times daily f …
Data were analyzed from June through October 2018. INTERVENTIONS: Initiation at discharge of oxycodone hydrochloride 5 mg of 10 mg (i …
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Ilyas AM, Miller AJ, Graham JG, Matzon JL. Ilyas AM, et al. Orthopedics. 2019 Mar 1;42(2):110-115. doi: 10.3928/01477447-20190221-02. Epub 2019 Feb 27. Orthopedics. 2019. PMID: 30810754 Clinical Trial.
The goal of this study was to evaluate 3 common oral analgesics-oxycodone (OXY), ibuprofen (IBU), and acetaminophen (ACE)-for pain management following carpal tunnel release (CTR) and trigger finger release (TFR) surgery. ...
The goal of this study was to evaluate 3 common oral analgesics-oxycodone (OXY), ibuprofen (IBU), and acetaminophen (ACE)-for …
Pain Management After Carpal Tunnel Release Surgery: A Prospective Randomized Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone.
Ilyas AM, Miller AJ, Graham JG, Matzon JL. Ilyas AM, et al. J Hand Surg Am. 2018 Oct;43(10):913-919. doi: 10.1016/j.jhsa.2018.08.011. J Hand Surg Am. 2018. PMID: 30286851 Clinical Trial.
The purpose of this study was to determine if there was a difference in pain levels or pill consumption when using nonopioids, ibuprofen (IBU) and acetaminophen (ACE), versus an opioid, oxycodone (OXY), after carpal tunnel release (CTR) performed exclusively under l …
The purpose of this study was to determine if there was a difference in pain levels or pill consumption when using nonopioids, ibuprofen (IB …
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
Friedman BW, Dym AA, Davitt M, Holden L, Solorzano C, Esses D, Bijur PE, Gallagher EJ. Friedman BW, et al. JAMA. 2015 Oct 20;314(15):1572-80. doi: 10.1001/jama.2015.13043. JAMA. 2015. PMID: 26501533 Clinical Trial.
At baseline, median RMDQ score in the placebo group was 20 (interquartile range [IQR],17-21), in the cyclobenzaprine group 19 (IQR,17-21), and in the oxycodone/acetaminophen group 20 (IQR,17-22). At 1-week follow-up, the mean RMDQ improvement was 9.8 in the placebo …
At baseline, median RMDQ score in the placebo group was 20 (interquartile range [IQR],17-21), in the cyclobenzaprine group 19 (IQR,17-21), a …
A randomized controlled trial of oxycodone/acetaminophen versus acetaminophen alone for emergency department patients with musculoskeletal pain refractory to ibuprofen.
Friedman BW, Irizarry E, Feliciano C, Izzo AJ, Borrayes L, Restivo A, Costa V, Bijur PE. Friedman BW, et al. Acad Emerg Med. 2021 Aug;28(8):859-865. doi: 10.1111/acem.14231. Epub 2021 Mar 12. Acad Emerg Med. 2021. PMID: 33576545 Free article. Clinical Trial.
A total of 159 (40%) patients reported inadequate relief after 1 h had elapsed. A total of 154 of these were randomized, 77 to oxycodone/acetaminophen and 77 to acetaminophen. Baseline characteristics were comparable. Among patients randomized to oxycodone …
A total of 159 (40%) patients reported inadequate relief after 1 h had elapsed. A total of 154 of these were randomized, 77 to oxycodone …
Morphine Versus Oxycodone for Cancer Pain Using a Catechol-O-methyltransferase Genotype Biomarker: A Multicenter, Randomized, Open-Label, Phase III Clinical Trial (RELIEF Study).
Matsuoka H, Tsurutani J, Chiba Y, Fujita Y, Sakai K, Yoshida T, Nakura M, Sakamoto R, Makimura C, Ohtake Y, Tanaka K, Hayashi H, Takeda M, Okuno T, Takegawa N, Haratani K, Koyama A, Nishio K, Nakagawa K. Matsuoka H, et al. Oncologist. 2023 Mar 17;28(3):278-e166. doi: 10.1093/oncolo/oyac233. Oncologist. 2023. PMID: 36426809 Free PMC article. Clinical Trial.
Patients with cancer pain treated with regular doses of nonsteroidal anti-inflammatory drugs or acetaminophen were enrolled and randomized (1:1) into morphine (group M) and oxycodone (group O) groups. ...CONCLUSION: Using the COMT rs4680 genotype alone is not recomm …
Patients with cancer pain treated with regular doses of nonsteroidal anti-inflammatory drugs or acetaminophen were enrolled and rando …
Oxycodone-acetaminophen versus celecoxib for postoperative pain in knee osteoarthritis patients after total knee arthroplasty: a randomized, controlled study.
Li Y, An M, Ding Y, Wang C, Qiu Y. Li Y, et al. Arch Orthop Trauma Surg. 2023 Nov;143(11):6753-6762. doi: 10.1007/s00402-023-04943-6. Epub 2023 Jun 21. Arch Orthop Trauma Surg. 2023. PMID: 37344688 Clinical Trial.

Besides, extra (P < 0.001) and total (P < 0.001) PCA consumption were declined in oxycodone-acetaminophen group compared with celecoxib group. Furthermore, patients' satisfaction score at D3 (P = 0.012) and D7 (P = 0.043) was higher in oxycodone-acet

…

Besides, extra (P < 0.001) and total (P < 0.001) PCA consumption were declined in oxycodone-acetaminophen group compared

…
Multi-Modal Pain Control in Ambulatory Hand Surgery.
Harrison RK, DiMeo T, Klinefelter RD, Ruff ME, Awan HM. Harrison RK, et al. Am J Orthop (Belle Mead NJ). 2018 Jun;47(6). doi: 10.12788/ajo.2018.0042. Am J Orthop (Belle Mead NJ). 2018. PMID: 29979803 Clinical Trial.
A prospective, randomized study of 79 patients undergoing elective CMC arthroplasty or ORIF of the distal radius evaluated postoperative pain in the first 5 postoperative days. Patients were divided into 4 groups: Group 1, oxycodone and acetaminophen PRN; Group 2, …
A prospective, randomized study of 79 patients undergoing elective CMC arthroplasty or ORIF of the distal radius evaluated postoperative pai …
Oral oxycodone plus intravenous acetaminophen versus intravenous morphine sulfate in acute bone fracture pain control: a double-blind placebo-controlled randomized clinical trial.
Zare MA, Ghalyaie AH, Fathi M, Farsi D, Abbasi S, Hafezimoghadam P. Zare MA, et al. Eur J Orthop Surg Traumatol. 2014 Oct;24(7):1305-9. doi: 10.1007/s00590-013-1392-x. Epub 2013 Dec 20. Eur J Orthop Surg Traumatol. 2014. PMID: 24356922 Clinical Trial.
Eight (10.8%) patients in morphine sulfate group and 26 (32.9%) patients in acetaminophen/oxycodone group experienced nausea that was statistically significant higher (P value = 0.001). Itching was seen in 12 (15.1%) patients of acetaminophen/oxycodone …
Eight (10.8%) patients in morphine sulfate group and 26 (32.9%) patients in acetaminophen/oxycodone group experienced nausea t …
211 results