Kininogen, High-Molecular-Weight
A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed)
Year introduced: 1998
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Subheadings:
Tree Number(s): D12.644.276.812.654.350, D12.776.124.125.635.480, D12.776.467.812.654.350, D12.776.811.420.350, D23.119.630.480, D23.469.050.375.425.350, D23.529.812.654.350
MeSH Unique ID: D019679
Entry Terms:
- Kininogen, High Molecular Weight
- High-Molecular-Weight Kininogen
- HMWK
- Fitzgerald Factor
- High Molecular Weight Kininogens
- Kininogens, High Molecular Weight
- High-Molecular-Weight Kininogens
- Kininogens, High-Molecular-Weight
- High Molecular Weight Kininogen
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