Caspase 8
A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.
Year introduced: 2007(2000)
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Subheadings:
Tree Number(s): D08.811.277.656.262.500.126.550.800, D08.811.277.656.300.200.126.550.800, D12.776.157.057.018.037, D12.776.476.024.320.025, D12.776.476.075.405.550.800, D12.776.476.075.421.037
MeSH Unique ID: D053181
Registry Number: EC 3.4.22.-
Entry Terms:
- CAP4 Protease
- FLICE Protein
- MACH Protein
- Mch5 Protease
- Caspase-8
- Procaspase-8
- Procaspase 8
- Pro-Caspase-8
- Pro Caspase 8
See Also: