Trends Cell Biol. 1998 Dec;8(12):467-70.

Nuclear migration, nucleokinesis and lissencephaly.

Source

Dept of Pharmacology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, USA. morrisnr@rwja.umdnj.edu

Abstract

During the past 20 years, biologists have become used to finding that proteins first identified in simple, genetically manipulable eukaryotic organisms are conserved in higher eukaryotes. This article draws attention to the similarity between NUDF protein, which is required for nuclear migration in the filamentous fungus Aspergillus nidulans, and a mammalian homologue, LIS1, whose malfunction causes lissencephaly, a neuronal migration disease. The authors suggest that there might be an underlying similarity of mechanism between nuclear migration in the fungus and neuronal migration in the brain.

PMID:: 9861667; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

GM 52309/GM/NIGMS NIH HHS/United States

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration. [Mol Biol Cell. 1995]
NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration.
Xiang X, Osmani AH, Osmani SA, Xin M, Morris NR. Mol Biol Cell. 1995 Mar; 6(3):297-310.
The LIS1-related NUDF protein of Aspergillus nidulans interacts with the coiled-coil domain of the NUDE/RO11 protein. [J Cell Biol. 2000]
The LIS1-related NUDF protein of Aspergillus nidulans interacts with the coiled-coil domain of the NUDE/RO11 protein.
Efimov VP, Morris NR. J Cell Biol. 2000 Aug 7; 150(3):681-8.
The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC. [Curr Biol. 1998]
The lissencephaly gene product Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC.
Morris SM, Albrecht U, Reiner O, Eichele G, Yu-Lee LY. Curr Biol. 1998 May 7; 8(10):603-6.
Review Lissencephaly and LIS1: insights into the molecular mechanisms of neuronal migration and development. [Clin Genet. 2007]
Review Lissencephaly and LIS1: insights into the molecular mechanisms of neuronal migration and development.
Wynshaw-Boris A. Clin Genet. 2007 Oct; 72(4):296-304.
Review Neuronal migration. [Mech Dev. 2001]
Review Neuronal migration.
Lambert de Rouvroit C, Goffinet AM. Mech Dev. 2001 Jul; 105(1-2):47-56.

See reviews... See all...

Cited by 27 PubMed Central articles

Review Adult neurogenesis: examples from the decapod crustaceans and comparisons with mammals. [Arthropod Struct Dev. 2011]
Review Adult neurogenesis: examples from the decapod crustaceans and comparisons with mammals.
Sandeman DC, Bazin F, Beltz BS. Arthropod Struct Dev. 2011 May; 40(3):258-75. Epub 2011 Mar 9.
Platelet activating factor blocks interkinetic nuclear migration in retinal progenitors through an arrest of the cell cycle at the S/G2 transition. [PLoS One. 2011]
Platelet activating factor blocks interkinetic nuclear migration in retinal progenitors through an arrest of the cell cycle at the S/G2 transition.
Fragel-Madeira L, Meletti T, Mariante RM, Monteiro RQ, Einicker-Lamas M, Bernardo RR, Lopes AH, Linden R. PLoS One. 2011 Jan 27; 6(1):e16058. Epub 2011 Jan 27.
Rab-mediated vesicular transport is required for neuronal positioning in the developing Drosophila visual system. [Mol Brain. 2010]
Rab-mediated vesicular transport is required for neuronal positioning in the developing Drosophila visual system.
Houalla T, Shi L, van Meyel DJ, Rao Y. Mol Brain. 2010 Jun 11; 3:19. Epub 2010 Jun 11.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Nuclear migration, nucleokinesis and lissencephaly.
Nuclear migration, nucleokinesis and lissencephaly.
Trends Cell Biol. 1998 Dec ;8(12):467-70.

PubMed
Iontophoretically applied corticosteroids do not affect the firing of hippocampa...
Iontophoretically applied corticosteroids do not affect the firing of hippocampal neurons.
Neuroendocrinology. 1977 ;23(4):248-56.

PubMed
Dose-response cocaine pharmacokinetics and metabolite profile following intraven...
Dose-response cocaine pharmacokinetics and metabolite profile following intravenous administration and arterial sampling in unanesthetized, freely moving male rats.
Neurotoxicol Teratol. 1997 Jan-Feb ;19(1):7-15.

PubMed
Rat hippocampal neurons in dispersed cell culture.
Rat hippocampal neurons in dispersed cell culture.
Brain Res. 1977 May 13 ;126(3):397-42.

PubMed
NMDA receptor antagonists impair prefrontal cortex function as assessed via spat...
NMDA receptor antagonists impair prefrontal cortex function as assessed via spatial delayed alternation performance in rats: modulation by dopamine.
J Neurosci. 1996 Jan ;16(1):373-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Nuclear migration, nucleokinesis and lissencephaly.

Source

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

Research Materials

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 27 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information