Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14729-32.

Cleavage planes in frog eggs are altered by strong magnetic fields.

Denegre JM, Valles JM Jr, Lin K, Jordan WB, Mowry KL.

Source

Department of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI 02912, USA.

Abstract

Early cleavages of Xenopus embryos were oriented in strong, static magnetic fields. Third-cleavage planes, normally horizontal, were seen to orient to a vertical plane parallel with a vertical magnetic field. Second cleavages, normally vertical, could also be oriented by applying a horizontal magnetic field. We argue that these changes in cleavage-furrow geometries result from changes in the orientation of the mitotic apparatus. We hypothesize that the magnetic field acts directly on the microtubules of the mitotic apparatus. Considerations of the length of the astral microtubules, their diamagnetic anisotropy, and flexural rigidity predict the required field strength for an effect that agrees with the data. This observation provides a clear example of a static magnetic-field effect on a fundamental cellular process, cell division.

PMID:: 9843957; [PubMed - indexed for MEDLINE]
PMCID:: PMC24517

Free PMC Article

Publication Types, MeSH Terms

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Cleavage and survival of Xenopus embryos exposed to 8 T static magnetic fields in a rotating clinostat. [Bioelectromagnetics. 2006]
Cleavage and survival of Xenopus embryos exposed to 8 T static magnetic fields in a rotating clinostat.
Eguchi Y, Ueno S, Kaito C, Sekimizu K, Shiokawa K. Bioelectromagnetics. 2006 May; 27(4):307-13.
Processes that occur before second cleavage determine third cleavage orientation in Xenopus. [Exp Cell Res. 2002]
Processes that occur before second cleavage determine third cleavage orientation in Xenopus.
Valles JM Jr, Wasserman SR, Schweidenback C, Edwardson J, Denegre JM, Mowry KL. Exp Cell Res. 2002 Mar 10; 274(1):112-8.
Model of magnetic field-induced mitotic apparatus reorientation in frog eggs. [Biophys J. 2002]
Model of magnetic field-induced mitotic apparatus reorientation in frog eggs.
Valles JM Jr. Biophys J. 2002 Mar; 82(3):1260-5.
Review Magnetic field effects on biomolecules, cells, and living organisms. [Biosystems. 1995]
Review Magnetic field effects on biomolecules, cells, and living organisms.
Hong FT. Biosystems. 1995; 36(3):187-229.
Review Effects of static magnetic fields at the cellular level. [Prog Biophys Mol Biol. 2005]
Review Effects of static magnetic fields at the cellular level.
Miyakoshi J. Prog Biophys Mol Biol. 2005 Feb-Apr; 87(2-3):213-23.

See reviews... See all...

Cited by 6 PubMed Central articles

Microgravity simulation by diamagnetic levitation: effects of a strong gradient magnetic field on the transcriptional profile of Drosophila melanogaster. [BMC Genomics. 2012]
Microgravity simulation by diamagnetic levitation: effects of a strong gradient magnetic field on the transcriptional profile of Drosophila melanogaster.
Herranz R, Larkin OJ, Dijkstra CE, Hill RJ, Anthony P, Davey MR, Eaves L, van Loon JJ, Medina FJ, Marco R. BMC Genomics. 2012 Feb 1; 13:52. Epub 2012 Feb 1.
Recovery Effects of a 180 mT Static Magnetic Field on Bone Mineral Density of Osteoporotic Lumbar Vertebrae in Ovariectomized Rats. [Evid Based Complement Alternat...]
Recovery Effects of a 180 mT Static Magnetic Field on Bone Mineral Density of Osteoporotic Lumbar Vertebrae in Ovariectomized Rats.
Xu S, Okano H, Tomita N, Ikada Y. Evid Based Complement Alternat Med. 2011; 2011. Epub 2010 Sep 28.
High magnetic field induced changes of gene expression in arabidopsis. [Biomagn Res Technol. 2006]
High magnetic field induced changes of gene expression in arabidopsis.
Paul AL, Ferl RJ, Meisel MW. Biomagn Res Technol. 2006 Dec 22; 4:7. Epub 2006 Dec 22.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Cleavage planes in frog eggs are altered by strong magnetic fields.
Cleavage planes in frog eggs are altered by strong magnetic fields.
Proc Natl Acad Sci U S A. 1998 Dec 8 ;95(25):14729-32.

PubMed
Part IV: visual determination of generators of the magnetocardiogram.
Part IV: visual determination of generators of the magnetocardiogram.
J Electrocardiol. 1976 ;9(4):426-32.

PubMed
Association of guide RNA binding protein gBP21 with active RNA editing complexes...
Association of guide RNA binding protein gBP21 with active RNA editing complexes in Trypanosoma brucei.
Mol Cell Biol. 1998 Oct ;18(10):6014-22.

PubMed
The macromolecular composition of Xenopus laevis egg jelly coat.
The macromolecular composition of Xenopus laevis egg jelly coat.
Biochemistry. 1975 Jul 15 ;14(14):3101-7.

PubMed
Tethered bandshift assay and affinity purification of a new DNA-binding protein.
Tethered bandshift assay and affinity purification of a new DNA-binding protein.
Biotechniques. 1994 May ;16(5):852-5.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: