Source
Center of Nutrition and Metabolism, Metro Health Medical Center, Department of Medicine, Case Western Reserve University, Cleveland, Ohio 44109-1998, USA.
Abstract
OBJECTIVE: The objective of this work was to develop practice guidelines for the management of alcoholic liver disease. METHOD: A computerized search using the Medline Data Base from 1966-July 1997 was performed with the search headings; alcohol, alcoholic hepatitis, alcoholic liver disease, liver transplant, diagnosis, epidemiology, human, and English only. All randomized controlled trials, case-control studies, and meta-analyses were read in depth. A manual search was also done using references from each retrieved report, review articles, editorials, postgraduate course syllabi, and textbooks. In the subsequent review, evidence was evaluated using a hierarchical scale with randomized, controlled trials given the most importance. Abstracts presented at national meetings were included only when unique data were obtained from those studies.