Chem Biol. 1998 Sep;5(9):R215-20.

Rhyme or reason: RNA-arginine interactions and the genetic code.

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Department of Ecology and Evolutionary Biology, Princeton University, NJ 08544-1003, USA.

Abstract

Theories about the origin of the genetic code require specific recognition between nucleic acids and amino acids at some stage of the code's evolution. A statistical analysis of arginine-binding RNA aptamers now offers the opportunity to test such interactions and provides the strongest support for an intrinsic affinity between any amino acid and its codons.

PMID:: 9751648; [PubMed - indexed for MEDLINE]

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Rhyme or reason: RNA-arginine interactions and the genetic code.

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