JAMA. 1976 Feb 23;235(8):839-40.

Amelioration of insulin lipoatrophy by dexamethasone injection.

Abstract

Widespread subcutaneous lipoatrophy occurred in a 47-year-old woman after subcutaneous injections of isophane insulin suspension for five months. Subsequent systemic treatment with a dexamethasone (0.08 mg/day) insulin mixture injected subcutaneously into the depressed areas resulted in an impressive return of subcutaneous tissue after eight months of continuous therapy.

PMID:: 946314; [PubMed - indexed for MEDLINE]

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Successful treatment of insulin lipoatrophy. A case report. [Diabete Metab. 1979]
Successful treatment of insulin lipoatrophy. A case report.
Asherov J, Mimouni M, Laron Z. Diabete Metab. 1979 Mar; 5(1):1-3.
Use of dexamethasone in treatment of insulin lipoatrophy. [Diabetes. 1977]
Use of dexamethasone in treatment of insulin lipoatrophy.
Kumar O, Miller L, Mehtalia S. Diabetes. 1977 Apr; 26(4):296-9.
Continuous subcutaneous insulin infusion (CSII) in the management of diabetic lipodystrophy: a case report. [Acta Diabetol Lat. 1987]
Continuous subcutaneous insulin infusion (CSII) in the management of diabetic lipodystrophy: a case report.
Cimino A, Valentini U, Rotondi A, Radaeli E, Giustina G. Acta Diabetol Lat. 1987 Apr-Jun; 24(2):165-7.
Review Skin-related complications of insulin therapy: epidemiology and emerging management strategies. [Am J Clin Dermatol. 2003]
Review Skin-related complications of insulin therapy: epidemiology and emerging management strategies.
Richardson T, Kerr D. Am J Clin Dermatol. 2003; 4(10):661-7.
Review Lipodystrophy reactions to insulin: effects of continuous insulin infusion and new insulin analogs. [Am J Clin Dermatol. 2007]
Review Lipodystrophy reactions to insulin: effects of continuous insulin infusion and new insulin analogs.
Radermecker RP, Piérard GE, Scheen AJ. Am J Clin Dermatol. 2007; 8(1):21-8.

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Cited by 1 PubMed Central article

Relapsing insulin-induced lipoatrophy, cured by prolonged low-dose oral prednisone: a case report. [Diabetol Metab Syndr. 2011]
Relapsing insulin-induced lipoatrophy, cured by prolonged low-dose oral prednisone: a case report.
Chantelau EA, Praetor R, Praetor J, Poll LW. Diabetol Metab Syndr. 2011 Dec 6; 3(1):33. Epub 2011 Dec 6.

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Amelioration of insulin lipoatrophy by dexamethasone injection.

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