Psychiatr Genet. 1995 Fall;5(3):117-26.

Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32.

Lin MW, Curtis D, Williams N, Arranz M, Nanko S, Collier D, McGuffin P, Murray R, Owen M, Gill M, et al.

Source

Department of Neuroscience and Psychological Medicine, Institute of Psychiatry, London, UK.

Erratum in

Psychiatr Genet 1996 Spring;6(1):37.

Abstract

Family, twin and adoption studies highlight the influence of genes in the aetiology of schizophrenia, though the mode of inheritance is unclear. We have been conducting a systematic search for major genes in schizophrenia using a series of multiply affected families and report preliminary results of linkage under heterogeneity with markers on chromosome 13. A lod2 score of 1.61 for marker D13S144 was obtained at theta = 0 and alpha of 0.5 and nearby markers also produced positive values.

PMID:: 8746410; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

A study of chromosome 4p markers and dopamine D5 receptor gene in schizophrenia and bipolar disorder. [Mol Psychiatry. 1998]
A study of chromosome 4p markers and dopamine D5 receptor gene in schizophrenia and bipolar disorder.
Asherson P, Mant R, Williams N, Cardno A, Jones L, Murphy K, Collier DA, Nanko S, Craddock N, Morris S, et al. Mol Psychiatry. 1998 Jul; 3(4):310-20.
Suggestive evidence for linkage of schizophrenia to markers on chromosome 13 in Caucasian but not Oriental populations. [Hum Genet. 1997]
Suggestive evidence for linkage of schizophrenia to markers on chromosome 13 in Caucasian but not Oriental populations.
Lin MW, Sham P, Hwu HG, Collier D, Murray R, Powell JF. Hum Genet. 1997 Mar; 99(3):417-20.
Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23. [Am J Hum Genet. 2001]
Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23.
Gurling HM, Kalsi G, Brynjolfson J, Sigmundsson T, Sherrington R, Mankoo BS, Read T, Murphy P, Blaveri E, McQuillin A, et al. Am J Hum Genet. 2001 Mar; 68(3):661-73.
Review A linkage study of schizophrenia with DNA markers from the long arm of chromosome 11. [Psychol Med. 1993]
Review A linkage study of schizophrenia with DNA markers from the long arm of chromosome 11.
Gill M, McGuffin P, Parfitt E, Mant R, Asherson P, Collier D, Vallada H, Powell J, Shaikh S, Taylor C. Psychol Med. 1993 Feb; 23(1):27-44.
Review Genetic linkage and schizophrenia: methods, recent findings and future directions. [Aust N Z J Psychiatry. 1993]
Review Genetic linkage and schizophrenia: methods, recent findings and future directions.
Mowry BJ, Levinson DF. Aust N Z J Psychiatry. 1993 Jun; 27(2):200-18.

See reviews... See all...

Cited by 10 PubMed Central articles

Elucidating the genetic architecture of familial schizophrenia using rare copy number variant and linkage scans. [Proc Natl Acad Sci U S A. 2009]
Elucidating the genetic architecture of familial schizophrenia using rare copy number variant and linkage scans.
Xu B, Woodroffe A, Rodriguez-Murillo L, Roos JL, van Rensburg EJ, Abecasis GR, Gogos JA, Karayiorgou M. Proc Natl Acad Sci U S A. 2009 Sep 29; 106(39):16746-51. Epub 2009 Sep 11.
Evidence for the association of the DAOA (G72) gene with schizophrenia and bipolar disorder but not for the association of the DAO gene with schizophrenia. [Behav Brain Funct. 2009]
Evidence for the association of the DAOA (G72) gene with schizophrenia and bipolar disorder but not for the association of the DAO gene with schizophrenia.
Bass NJ, Datta SR, McQuillin A, Puri V, Choudhury K, Thirumalai S, Lawrence J, Quested D, Pimm J, Curtis D, et al. Behav Brain Funct. 2009 Jul 8; 5:28. Epub 2009 Jul 8.
Review Molecular genetics of schizophrenia: a critical review. [J Psychiatry Neurosci. 2003]
Review Molecular genetics of schizophrenia: a critical review.
Berry N, Jobanputra V, Pal H. J Psychiatry Neurosci. 2003 Nov; 28(6):415-29.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Gene (OMIM)
Gene records associated with Online Mendelian Inheritance in Man (OMIM) records that cite the current articles in their reference lists.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
OMIM (cited)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as reference cited at the end of the OMIM record.
UniSTS
Genetic, physical, and sequence mapping reagents in the UniSTS database associated with the current articles through references on sequence tagged site (STS) submissions as well as automated searching of PubMed abstracts and full-text PubMed Central articles for marker names.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14....
Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32.
Psychiatr Genet. 1995 Fall ;5(3):117-26.

PubMed
Enhancement of the bioavailability of propranolol and metoprolol by food.
Enhancement of the bioavailability of propranolol and metoprolol by food.
Clin Pharmacol Ther. 1977 Jul ;22(1):108-12.

PubMed
Folic acid and prevention of neural tube defects: a study of Canadian mothers of...
Folic acid and prevention of neural tube defects: a study of Canadian mothers of infants with spina bifida.
Clin Invest Med. 1996 Jun ;19(3):195-201.

PubMed
Preoperative irradiation in operable cancer of the rectum: report of the Toronto...
Preoperative irradiation in operable cancer of the rectum: report of the Toronto trial.
Can J Surg. 1977 Jul ;20(4):335-8.

PubMed
End-stage renal disease in the USA: data from the United States Renal Data Syste...
End-stage renal disease in the USA: data from the United States Renal Data System.
Am J Nephrol. 1996 ;16(1):7-16.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32.

Source

Erratum in

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 10 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information