Diabetes. 1977 Apr;26(4):296-9.

Use of dexamethasone in treatment of insulin lipoatrophy.

Abstract

To treat insulin lipoatrophy, small amounts of dexamethasone (4 micrograms/unit) were added to insulin injections in nine patients. Six cases showed significant improvement of dexamethasone-treated sites over that of control sites in six months. With the continued use of dexamethasone-containing insulin, they remained mostly free of atrophic areas during the follow-up period of over two years. Our experience suggests the usefulness of this therapy.

PMID:: 849810; [PubMed - indexed for MEDLINE]

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Amelioration of insulin lipoatrophy by dexamethasone injection. [JAMA. 1976]
Amelioration of insulin lipoatrophy by dexamethasone injection.
Whitley TH, Lawrence PA, Smith CL. JAMA. 1976 Feb 23; 235(8):839-40.
Treatment of insulin-induced lipoatrophy. [Diabetes. 1976]
Treatment of insulin-induced lipoatrophy.
Hulst SG. Diabetes. 1976 Nov; 25(11):1052-4.
Controlled study comparing treatment with monocomponent insulin and conventional insulin in patients with lipoatrophy. [Acta Diabetol Lat. 1989]
Controlled study comparing treatment with monocomponent insulin and conventional insulin in patients with lipoatrophy.
Czyzyk A, Rogala H, Lawecki J. Acta Diabetol Lat. 1989 Jan-Mar; 26(1):17-26.
Review Skin-related complications of insulin therapy: epidemiology and emerging management strategies. [Am J Clin Dermatol. 2003]
Review Skin-related complications of insulin therapy: epidemiology and emerging management strategies.
Richardson T, Kerr D. Am J Clin Dermatol. 2003; 4(10):661-7.
Review New forms of insulin and their use in the treatment of diabetes. [Diabetes. 1977]
Review New forms of insulin and their use in the treatment of diabetes.
Yue DK, Turtle JR. Diabetes. 1977 Apr; 26(4):341-5.

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Cited by 2 PubMed Central articles

Relapsing insulin-induced lipoatrophy, cured by prolonged low-dose oral prednisone: a case report. [Diabetol Metab Syndr. 2011]
Relapsing insulin-induced lipoatrophy, cured by prolonged low-dose oral prednisone: a case report.
Chantelau EA, Praetor R, Praetor J, Poll LW. Diabetol Metab Syndr. 2011 Dec 6; 3(1):33. Epub 2011 Dec 6.
Insulin-induced lipoatrophy: evidence for an immune pathogenesis. [Br Med J. 1980]
Insulin-induced lipoatrophy: evidence for an immune pathogenesis.
Reeves WG, Allen BR, Tattersall RB. Br Med J. 1980 Jun 21; 280(6230):1500-3.

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Use of dexamethasone in treatment of insulin lipoatrophy.

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