J Histochem Cytochem. 1993 Aug;41(8):1253-7.

Establishment of a novel monoclonal antibody, SE-1, which specifically reacts with rat hepatic sinusoidal endothelial cells.

Ohmura T, Enomoto K, Satoh H, Sawada N, Mori M.

Source

Department of Pathology, Sapporo Medical College, Japan.

Abstract

A monoclonal antibody, SE-1, which specifically reacted with rat hepatic sinusoidal endothelial cells (HSE), was established with elutriator-separated HSE as immunogen. No crossreactivity was observed with other types of endothelial cells or non-endothelial cells. By immunoelectron microscopy, the antigen recognized by MAb SE-1 was localized to the membrane surface of HSE. Immunoblot analysis revealed that SE-1 recognized a single 45 KD band. Although the SE-1 antigen is not yet characterized, the above evidence strongly suggests that it is related to the specific function of HSE. Therefore, SE-1 may be a useful marker to study the role of HSE in various pathophysiological conditions of the liver.

PMID:: 8331290; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

Substances

Antibodies, Monoclonal

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

Analysis of the sinusoidal endothelial cell organization during the developmental stage of the fetal rat liver using a sinusoidal endothelial cell specific antibody, SE-1. [Cell Struct Funct. 1998]
Analysis of the sinusoidal endothelial cell organization during the developmental stage of the fetal rat liver using a sinusoidal endothelial cell specific antibody, SE-1.
Morita M, Qun W, Watanabe H, Doi Y, Mori M, Enomoto K. Cell Struct Funct. 1998 Dec; 23(6):341-8.
Production of two novel monoclonal antibodies that distinguish mouse lymphatic and blood vascular endothelial cells. [Anat Embryol (Berl). 2006]
Production of two novel monoclonal antibodies that distinguish mouse lymphatic and blood vascular endothelial cells.
Ezaki T, Kuwahara K, Morikawa S, Shimizu K, Sakaguchi N, Matsushima K, Matsuno K. Anat Embryol (Berl). 2006 Oct; 211(5):379-93. Epub 2006 May 10.
Identification of a novel high molecular weight protein preferentially expressed by sinusoidal endothelial cells in normal human tissues. [J Cell Biol. 1991]
Identification of a novel high molecular weight protein preferentially expressed by sinusoidal endothelial cells in normal human tissues.
Goerdt S, Walsh LJ, Murphy GF, Pober JS. J Cell Biol. 1991 Jun; 113(6):1425-37.
Review Cooperation of liver cells in health and disease. [Adv Anat Embryol Cell Biol. 2001]
Review Cooperation of liver cells in health and disease.
Kmieć Z. Adv Anat Embryol Cell Biol. 2001; 161:III-XIII, 1-151.
Review Regulatory mechanisms of hepatic microcirculation. [Clin Hemorheol Microcirc. 2003]
Review Regulatory mechanisms of hepatic microcirculation.
Oda M, Yokomori H, Han JY. Clin Hemorheol Microcirc. 2003; 29(3-4):167-82.

See reviews... See all...

Cited by 7 PubMed Central articles

3D hepatic cultures simultaneously maintain primary hepatocyte and liver sinusoidal endothelial cell phenotypes. [PLoS One. 2010]
3D hepatic cultures simultaneously maintain primary hepatocyte and liver sinusoidal endothelial cell phenotypes.
Kim Y, Rajagopalan P. PLoS One. 2010 Nov 12; 5(11):e15456. Epub 2010 Nov 12.
The vascular endothelial growth factor (VEGF) receptor-2 is a major regulator of VEGF-mediated salvage effect in murine acute hepatic failure. [J Angiogenes Res. 2010]
The vascular endothelial growth factor (VEGF) receptor-2 is a major regulator of VEGF-mediated salvage effect in murine acute hepatic failure.
Namisaki T, Yoshiji H, Noguchi R, Ikenaka Y, Kitade M, Kaji K, Shirai Y, Aihara Y, Yoshii J, Yanase K, et al. J Angiogenes Res. 2010 Aug 24; 2:16. Epub 2010 Aug 24.
Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro. [Hepatology. 2009]
Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro.
March S, Hui EE, Underhill GH, Khetani S, Bhatia SN. Hepatology. 2009 Sep; 50(3):920-8.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Establishment of a novel monoclonal antibody, SE-1, which specifically reacts wi...
Establishment of a novel monoclonal antibody, SE-1, which specifically reacts with rat hepatic sinusoidal endothelial cells.
J Histochem Cytochem. 1993 Aug ;41(8):1253-7.

PubMed
The prelymphatic pathways of the brain as revealed by cervical lymphatic obstruc...
The prelymphatic pathways of the brain as revealed by cervical lymphatic obstruction and the passage of particles.
Br J Exp Pathol. 1976 Apr ;57(2):179-88.

PubMed
Hydrogen peroxide-induced endothelial retraction is accompanied by a loss of the...
Hydrogen peroxide-induced endothelial retraction is accompanied by a loss of the normal spatial organization of endothelial cell adhesion molecules.
Am J Pathol. 1995 Sep ;147(3):627-41.

PubMed
Morphology of blood-brain interfaces.
Morphology of blood-brain interfaces.
Exp Eye Res. 1977 ;25 Suppl:1-25.

PubMed
Effects of a progesterone-releasing intrauterine contraceptive device on endomet...
Effects of a progesterone-releasing intrauterine contraceptive device on endometrial blood vessels: a morphometric study.
Am J Obstet Gynecol. 1981 Dec 1 ;141(7):821-7.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Establishment of a novel monoclonal antibody, SE-1, which specifically reacts with rat hepatic sinusoidal endothelial cells.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 7 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information