J Rheumatol. 1993 Jun;20(6):958-61.

Scleroderma following silicone implantation: a cumulative experience of 11 cases.

Source

Department of Medicine, Mt. Sinai School of Medicine, New York, NY.

Abstract

In the 3 years since the initial report of 5 patients who developed scleroderma in association with silicone breast implants, 6 additional silicone implant recipients have presented with scleroderma. Two of these patients received silicone chin implants. A total of 5 patients elected to remove their prostheses. Two patients have had marked improvement of cutaneous scleroderma. The other 3 patients, however, died secondary to progressive visceral involvement. This cumulative experience of 11 cases of scleroderma following silicone implantation suggests additional evidence of an association between the 2. Careful case control studies over an extended period of time are required to determine the incidence of this outcome.

Comment in

J Rheumatol. 1994 Nov;21(11):2169.

PMID:: 7726871; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Case Reports

MeSH Terms

Substances

Silicones

LinkOut - more resources

Medical

Scleroderma - MedlinePlus Health Information

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

The development of systemic sclerosis (scleroderma) following augmentation mammoplasty. [J Rheumatol. 1993]
The development of systemic sclerosis (scleroderma) following augmentation mammoplasty.
Appleton BE, Lee P. J Rheumatol. 1993 Jun; 20(6):1052-4.
Scleroderma after silicone augmentation mammoplasty. [JAMA. 1988]
Scleroderma after silicone augmentation mammoplasty.
Spiera H. JAMA. 1988 Jul 8; 260(2):236-8.
[Systemic scleroderma and scleroderma-like disease after silicone implants]. [Ugeskr Laeger. 1992]
[Systemic scleroderma and scleroderma-like disease after silicone implants].
Zachariae H, Zachariae E. Ugeskr Laeger. 1992 Aug 3; 154(32):2209-10.
Review Silicone gel filled breast implants and connective tissue disease: an overview. [J Rheumatol. 1994]
Review Silicone gel filled breast implants and connective tissue disease: an overview.
Spiera RF, Gibofsky A, Spiera H. J Rheumatol. 1994 Feb; 21(2):239-45.
Review Systemic sclerosis after augmentation mammoplasty with silicone implants. [Ann Intern Med. 1989]
Review Systemic sclerosis after augmentation mammoplasty with silicone implants.
Varga J, Schumacher HR, Jimenez SA. Ann Intern Med. 1989 Sep 1; 111(5):377-83.

See reviews... See all...

Cited by 3 PubMed Central articles

Review Why are women predisposed to autoimmune rheumatic diseases? [Arthritis Res Ther. 2009]
Review Why are women predisposed to autoimmune rheumatic diseases?
Oliver JE, Silman AJ. Arthritis Res Ther. 2009; 11(5):252. Epub 2009 Oct 26.
Risk of cancer in patients with scleroderma. [Ann Rheum Dis. 2003]
Risk of cancer in patients with scleroderma.
Pearson JE, Silman AJ. Ann Rheum Dis. 2003 Aug; 62(8):697-9.
Silicone gel breast implant adverse event reports to the Food and Drug Administration, 1984-1995. [Public Health Rep. 1998]
Silicone gel breast implant adverse event reports to the Food and Drug Administration, 1984-1995.
Brown SL, Parmentier CM, Woo EK, Vishnuvajjala RL, Headrick ML. Public Health Rep. 1998 Nov-Dec; 113(6):535-43.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Scleroderma following silicone implantation: a cumulative experience of 11 cases...
Scleroderma following silicone implantation: a cumulative experience of 11 cases.
J Rheumatol. 1993 Jun ;20(6):958-61.

PubMed
Glucocorticosteroid therapy: mechanisms of action and clinical considerations.
Glucocorticosteroid therapy: mechanisms of action and clinical considerations.
Ann Intern Med. 1976 Mar ;84(3):304-15.

PubMed
Lifestyle and biologic factors associated with atherosclerotic disease in middle...
Lifestyle and biologic factors associated with atherosclerotic disease in middle-aged men. 20-year findings from the Honolulu Heart Program.
Arch Intern Med. 1995 Apr 10 ;155(7):686-94.

PubMed
Familial Sjögren's syndrome with associated primary salivary gland lymphoma.
Familial Sjögren's syndrome with associated primary salivary gland lymphoma.
Am J Med. 1976 Feb ;60(2):286-92.

PubMed
Human herpesviruses 6 and 7 in salivary glands and shedding in saliva of healthy...
Human herpesviruses 6 and 7 in salivary glands and shedding in saliva of healthy and human immunodeficiency virus positive individuals.
J Med Virol. 1995 Apr ;45(4):462-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: