Am J Hum Genet. 1981 Jan;33(1):36-43.

Biochemical genetics of glutathione-S-transferase in man.

Abstract

Glutathione-S-transferases from liver and erythrocytes have been separated by starch gel electrophoresis and localized by a specific staining procedure. The data suggest that the most active glutathione-S-transferases in liver are the products of two autosomal loci, GST1 and GST2. Both these loci are polymorphic, and there is evidence that a common null allele exists at the GST1 locus. The glutathione-S-transferase expressed in erythrocytes is the product of a third locus, GST3, and is not polymorphic.

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PMCID: PMC1684881

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Glutathione Transferase

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