Trans R Soc Trop Med Hyg. 1980;74(6):738-42.

Studies on the use of a membrane feeding technique for infecting Anopheles gambiae with Plasmodium falciparum.

Abstract

An investigation was made of the optimum feeding time when using stirred membrane feeders for infecting Anopheles gambiae s.s. with Plasmodium falciparum. The aim was to stimulate the natural situation of direct feeding on a host and so enable the malaria susceptibility of different populations of A. gambiae to be assessed. 45 feeds were carried out on blood donated by P. falciparum gametocyte carriers. The results show that only patients with at least 300 gametocytes/mm3 are likely to produce a high infection in mosquitoes. There was a marked decline in infectivity over a 35-min period after bleeding and 10-min feeds gave the highest proportion of mosquitoes infected. The decline in infectivity could not be attributed solely to the fact that the gametocytes had become activated before ingestion by the mosquito, since the rate of activation in a feeder was found to be lower than the rate of loss of infectivity to mosquitoes. The possible applications of the technique are discussed.

PMID:: 7010696; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

Substances

Membranes, Artificial

LinkOut - more resources

Libraries

LinkOut Holdings

Supplemental Content

Related citations

Plasmodium falciparum malaria disease manifestations in humans and transmission to Anopheles gambiae: a field study in Western Kenya. [Parasitology. 2004]
Plasmodium falciparum malaria disease manifestations in humans and transmission to Anopheles gambiae: a field study in Western Kenya.
Gouagna LC, Ferguson HM, Okech BA, Killeen GF, Kabiru EW, Beier JC, Githure JI, Yan G. Parasitology. 2004 Mar; 128(Pt 3):235-43.
High gametocyte complexity and mosquito infectivity of Plasmodium falciparum in the Gambia. [Int J Parasitol. 2008]
High gametocyte complexity and mosquito infectivity of Plasmodium falciparum in the Gambia.
Nwakanma D, Kheir A, Sowa M, Dunyo S, Jawara M, Pinder M, Milligan P, Walliker D, Babiker HA. Int J Parasitol. 2008 Feb; 38(2):219-27. Epub 2007 Jul 18.
Evaluation and optimization of membrane feeding compared to direct feeding as an assay for infectivity. [Malar J. 2008]
Evaluation and optimization of membrane feeding compared to direct feeding as an assay for infectivity.
Diallo M, Touré AM, Traoré SF, Niaré O, Kassambara L, Konaré A, Coulibaly M, Bagayogo M, Beier JC, Sakai RK, et al. Malar J. 2008 Dec 2; 7:248. Epub 2008 Dec 2.
Review Early sporogonic development in local vectors of Plasmodium falciparum in rural Cameroon. [Mem Inst Oswaldo Cruz. 1994]
Review Early sporogonic development in local vectors of Plasmodium falciparum in rural Cameroon.
Robert V, Le Goff G, Toto JC, Essong J, Verhave JP. Mem Inst Oswaldo Cruz. 1994; 89 Suppl 2:23-6.
Review The rise and fall of malarial sporozoite rates in Anopheles gambiae s.l. and An. funestus in north-eastern Tanzania, between 1934 and 1999. [Ann Trop Med Parasitol. 2001]
Review The rise and fall of malarial sporozoite rates in Anopheles gambiae s.l. and An. funestus in north-eastern Tanzania, between 1934 and 1999.
Mboera LE, Magesa SM. Ann Trop Med Parasitol. 2001 Jun; 95(4):325-30.

See reviews... See all...

Cited by 4 PubMed Central articles

Plasmodium vivax sporozoite production in Anopheles albimanus mosquitoes for vaccine clinical trials. [Am J Trop Med Hyg. 2011]
Plasmodium vivax sporozoite production in Anopheles albimanus mosquitoes for vaccine clinical trials.
Solarte Y, Manzano MR, Rocha L, Hurtado H, James MA, Arévalo-Herrera M, Herrera S. Am J Trop Med Hyg. 2011 Feb; 84(2 Suppl):28-34.
Consistent safety and infectivity in sporozoite challenge model of Plasmodium vivax in malaria-naive human volunteers. [Am J Trop Med Hyg. 2011]
Consistent safety and infectivity in sporozoite challenge model of Plasmodium vivax in malaria-naive human volunteers.
Herrera S, Solarte Y, Jordán-Villegas A, Echavarría JF, Rocha L, Palacios R, Ramírez O, Vélez JD, Epstein JE, Richie TL, et al. Am J Trop Med Hyg. 2011 Feb; 84(2 Suppl):4-11.
Human immune responses that reduce the transmission of Plasmodium falciparum in African populations. [Int J Parasitol. 2011]
Human immune responses that reduce the transmission of Plasmodium falciparum in African populations.
Bousema T, Sutherland CJ, Churcher TS, Mulder B, Gouagna LC, Riley EM, Targett GA, Drakeley CJ. Int J Parasitol. 2011 Mar; 41(3-4):293-300. Epub 2010 Oct 23.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Studies on the use of a membrane feeding technique for infecting Anopheles gambi...
Studies on the use of a membrane feeding technique for infecting Anopheles gambiae with Plasmodium falciparum.
Trans R Soc Trop Med Hyg. 1980 ;74(6):738-42.

PubMed
Evidence for an age-dependent pyrogenic threshold of Plasmodium falciparum paras...
Evidence for an age-dependent pyrogenic threshold of Plasmodium falciparum parasitemia in highly endemic populations.
Am J Trop Med Hyg. 1996 Jun ;54(6):613-9.

PubMed
Clinical trials of a new immunochromatographic test for diagnosis of Plasmodium ...
Clinical trials of a new immunochromatographic test for diagnosis of Plasmodium falciparum malaria in Goa.
Indian J Malariol. 1996 Dec ;33(4):166-72.

PubMed
Use of a low-speed, iso-density percoll centrifugation method to increase the vi...
Use of a low-speed, iso-density percoll centrifugation method to increase the viability of isolated rat hepatocyte preparations.
In Vitro Cell Dev Biol. 1986 Apr ;22(4):201-11.

PubMed
Predictors of mefloquine treatment failure: a prospective study of 1590 patients...
Predictors of mefloquine treatment failure: a prospective study of 1590 patients with uncomplicated falciparum malaria.
Trans R Soc Trop Med Hyg. 1995 Nov-Dec ;89(6):660-4.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

Studies on the use of a membrane feeding technique for infecting Anopheles gambiae with Plasmodium falciparum.

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Libraries

Supplemental Content

Related citations

Cited by 4 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information