Science. 1980 Sep 19;209(4463):1406-14.

Promoter sequences of eukaryotic protein-coding genes.

Corden J, Wasylyk B, Buchwalder A, Sassone-Corsi P, Kedinger C, Chambon P.

Abstract

In vitro genetic techniques were used to study the sequence requirements for the initiation of specific transcription. Deletion mutants were constructed around the putative promoter of the adenovirus-2 major late and chicken conalbumin genes. Specific transcription in vitro by RNA polymerase B together with a HeLa cell cytoplasmic extract was used as the test for promoter function. With this approach sequences which are essential for the initiation of specific transcription in vitro, were shown to be located between 12 and 32 base pairs upstream from the 5' end of these genes.

PMID:: 6251548; [PubMed - indexed for MEDLINE]

MeSH Terms, Substances

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Specific 5' flanking sequences are required for faithful initiation of in vitro transcription of the ovalbumin gene. [Proc Natl Acad Sci U S A. 1981]
Specific 5' flanking sequences are required for faithful initiation of in vitro transcription of the ovalbumin gene.
Tsai SY, Tsai MJ, O'Malley BW. Proc Natl Acad Sci U S A. 1981 Feb; 78(2):879-83.
In vitro transcription by purified yeast RNA polymerase II. Coarse promoter mapping on homologous cloned genes. [Nucleic Acids Res. 1982]
In vitro transcription by purified yeast RNA polymerase II. Coarse promoter mapping on homologous cloned genes.
Carnevali F, Caserta M, Di Mauro E. Nucleic Acids Res. 1982 May 25; 10(10):3195-209.
Promoter sequence of fibroin gene assigned by in vitro transcription system. [Proc Natl Acad Sci U S A. 1981]
Promoter sequence of fibroin gene assigned by in vitro transcription system.
Tsujimoto Y, Hirose S, Tsuda M, Suzuki Y. Proc Natl Acad Sci U S A. 1981 Aug; 78(8):4838-42.
Review [Promoters of eukaryotic genes transcribed by RNA polymerase II]. [Biochimie. 1982]
Review [Promoters of eukaryotic genes transcribed by RNA polymerase II].
Volovitch M. Biochimie. 1982 Oct; 64(10):III-VII.
Review Transcriptional control regions: nucleotide sequence requirements for initiation by RNA polymerase II and III. [Curr Top Microbiol Immunol. 1981]
Review Transcriptional control regions: nucleotide sequence requirements for initiation by RNA polymerase II and III.
Shenk T. Curr Top Microbiol Immunol. 1981; 93:25-46.

See reviews... See all...

Cited by over 100 PubMed Central articles

Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors. [PLoS One. 2012]
Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors.
Lützner N, De-Castro Arce J, Rösl F. PLoS One. 2012; 7(3):e32590. Epub 2012 Mar 6.
Structure, Expression, and Function of ICAM-5. [Comp Funct Genomics. 2012]
Structure, Expression, and Function of ICAM-5.
Yang H. Comp Funct Genomics. 2012; 2012:368938. Epub 2012 Jan 23.
Review Lysyl oxidase, a critical intra- and extra-cellular target in the lung for cigarette smoke pathogenesis. [Int J Environ Res Public Healt...]
Review Lysyl oxidase, a critical intra- and extra-cellular target in the lung for cigarette smoke pathogenesis.
Li W, Zhou J, Chen L, Luo Z, Zhao Y. Int J Environ Res Public Health. 2011 Jan; 8(1):161-84. Epub 2011 Jan 19.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Promoter sequences of eukaryotic protein-coding genes.
Promoter sequences of eukaryotic protein-coding genes.
Science. 1980 Sep 19 ;209(4463):1406-14.

PubMed
Why genes in pieces?
Why genes in pieces?
Nature. 1978 Feb 9 ;271(5645):501.

PubMed
Nucleotide sequence of bacteriophage lambda DNA.
Nucleotide sequence of bacteriophage lambda DNA.
J Mol Biol. 1982 Dec 25 ;162(4):729-73.

PubMed
Influence of water on protein structure. An analysis of the preferences of amino...
Influence of water on protein structure. An analysis of the preferences of amino acid residues for the inside or outside and for specific conformations in a protein molecule.
Macromolecules. 1978 Jan-Feb ;11(1):9-15.

PubMed
A selenocysteine-containing selenium-transport protein in rat plasma.
A selenocysteine-containing selenium-transport protein in rat plasma.
Biochim Biophys Acta. 1982 Oct 28 ;719(1):147-53.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: