J Cell Biol. 1978 Jan;76(1):175-83.

Lens differentiation. Crystallin synthesis in isolated epithelia from calf lenses.

Vermorken AJ, Hilderink JM, van de Ven WJ, Bloemendal H.

Abstract

In the calf eye lens, four morphologically distinct cell types can be detected: three in the epithelial monolayer and one in the cortical part. During differentiation, there is a quantitative change in the synthesis of crystallin subunits. A marked increase in alphaA-chains and several beta-crystallin polypeptides accompanies the transition from epithelial to fiberlike lens cells while synthesis of the non-crystallin proteins diminishes significantly.

PMID:: 618891; [PubMed - indexed for MEDLINE]
PMCID:: PMC2109957

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