Z Rheumatol. 1979 Jul-Aug;38(7-8):279-88.

Chronic synovitis with marked infiltration of granulocytes in a patient with an unusual development of systemic lupus erythematosus.

Meijers KA, Eulderink F, van de Putte LB, Wiersema-van Gogh H, de Vries E, Cats A.

Abstract

The case described concerns a patient initially presenting the clinical symptoms of rheumatoid arthritis, including the presence of nodules, and slowly developing into systemic lupus erythematosus (SLE). Besides the signs of chronic inflammation in the synovial tissue, many granulocytes and PAS-positive macrophages were present. At electronmicroscopy the basal membranes of the vessels were multilaminated and the endothelial cells enlarged while many macrophages contained large clumps of electrondense material which could easily be interpreted as rough endoplasmatic reticulum (RER) of plasma cells. Immunoflourescence studies showed deposition of immunoglobulins and complement in the vessel walls of the synovium, thus suggesting an immune-complex pathogenesis.

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Chronic synovitis with marked infiltration of granulocytes in a patient with an ...
Chronic synovitis with marked infiltration of granulocytes in a patient with an unusual development of systemic lupus erythematosus.
Z Rheumatol. 1979 Jul-Aug ;38(7-8):279-88.

PubMed
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Ann Intern Med. 1971 Jun ;74(6):911-21.

PubMed
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Genetic heterogeneity in osteogenesis imperfecta.
J Med Genet. 1979 Apr ;16(2):101-16.

PubMed
[Case of coexistence of rheumatoid arthritis and systemic lupus erythematosus].
[Case of coexistence of rheumatoid arthritis and systemic lupus erythematosus].
Pol Tyg Lek. 1973 Dec 10 ;28(50):1981-3.

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Determination of membrane thickness distribution from orthogonal intercepts.
Determination of membrane thickness distribution from orthogonal intercepts.
J Microsc. 1979 Jan ;115(1):19-33.

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