J Neurosci Res. 1979;4(1):59-64.

Intracellular studies of GABA and taurine action on the neurons of the cat sensorimotor cortex.

Abstract

The action of taurine and GABA on the cat cerebral cortex neurons was studied. Electrophoretically administered taurine and GABA hyperpolarized the neuron membrane. GABA, in contrast to taurine, sharply increased the somatic membrane conductance. Taurine action was weaker than that of GABA and its effects were not always observed. However, in a number of instances it exerted inhibitory influence similar to GABA action. Some facts make it possible to suppose that taurine acts mainly on the neuron dendrites. The data obtained are in accordance with the supposition that taurine might be an inhibitory transmitter in the cerebral cortex.

PMID:: 423315; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Comparative Study

MeSH Terms

Substances

LinkOut - more resources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

[Intracellular study of the effect of GABA and taurine on neurons of the sensomotor cortex in cats]. [Dokl Akad Nauk SSSR. 1978]
[Intracellular study of the effect of GABA and taurine on neurons of the sensomotor cortex in cats].
Aleksandrov AA. Dokl Akad Nauk SSSR. 1978; 241(6):1469-71.
[Increase in the sensitivity of rabbit sensomotor cortex neurons to gamma-aminobutyric acid under the influence of diazepam (microiontophoretic study)]. [Biull Eksp Biol Med. 1976]
[Increase in the sensitivity of rabbit sensomotor cortex neurons to gamma-aminobutyric acid under the influence of diazepam (microiontophoretic study)].
Kozhechkin SN, Ostrovskaia RU. Biull Eksp Biol Med. 1976 Dec; 82(12):1448-50.
[Microiontophoretic study of the effect of GABA and taurine on the activity of cat motor cortex neurons]. [Fiziol Zh SSSR Im I M Sechenov...]
[Microiontophoretic study of the effect of GABA and taurine on the activity of cat motor cortex neurons].
Aleksandrov AA. Fiziol Zh SSSR Im I M Sechenova. 1978 Aug; 64(8):1057-65.
[Effect of GABA and phenybut on the neuronal activity of the cortex and potentials of the spinal roots]. [Fiziol Zh SSSR Im I M Sechenov...]
[Effect of GABA and phenybut on the neuronal activity of the cortex and potentials of the spinal roots].
Aleksandrov AA, Van Nguyen U. Fiziol Zh SSSR Im I M Sechenova. 1977 Nov; 63(11):1505-10.
[Analysis of the plastic properties of the postsynaptic neuron in the sensory motor cortex in response to repeated microphoretic administration of gamma-aminobutyric acid]. [Nauchnye Doki Vyss Shkoly Biol...]
[Analysis of the plastic properties of the postsynaptic neuron in the sensory motor cortex in response to repeated microphoretic administration of gamma-aminobutyric acid].
Kotliar BI, Miasnikov AA, Kartaev SD, Norekian TP, Medvedovskiĭ BV. Nauchnye Doki Vyss Shkoly Biol Nauki. 1984; (9):52-6.

See reviews... See all...

Cited by 1 PubMed Central article

Reciprocal regulation between taurine and glutamate response via Ca2+-dependent pathways in retinal third-order neurons. [J Biomed Sci. 2010]
Reciprocal regulation between taurine and glutamate response via Ca2+-dependent pathways in retinal third-order neurons.
Bulley S, Shen W. J Biomed Sci. 2010 Aug 24; 17 Suppl 1:S5. Epub 2010 Aug 24.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound
PubChem chemical compound records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records. Multiple substance records may contribute to the PubChem compound record.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance
PubChem chemical substance records that cite the current articles. These references are taken from those provided on submitted PubChem chemical substance records.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Intracellular studies of GABA and taurine action on the neurons of the cat senso...
Intracellular studies of GABA and taurine action on the neurons of the cat sensorimotor cortex.
J Neurosci Res. 1979 ;4(1):59-64.

PubMed
Characteristics of the binding of the anticancer agents mitoxantrone and ametant...
Characteristics of the binding of the anticancer agents mitoxantrone and ametantrone and related structures to deoxyribonucleic acids.
Biochemistry. 1985 Jul 16 ;24(15):4028-35.

PubMed
Encephalomyocarditis virus-specific polypeptide p22 possessing a proteolytic act...
Encephalomyocarditis virus-specific polypeptide p22 possessing a proteolytic activity: preliminary mapping on the viral genome.
FEBS Lett. 1979 Dec 1 ;108(1):6-9.

PubMed
Regional distribution of M1, M2 and non-M1, non-M2 subtypes of muscarinic bindin...
Regional distribution of M1, M2 and non-M1, non-M2 subtypes of muscarinic binding sites in rat brain.
J Pharmacol Exp Ther. 1990 Dec ;255(3):1148-57.

PubMed
Effects of Doxycycline on gene expression in Wolbachia and Brugia malayi adult f...
Effects of Doxycycline on gene expression in Wolbachia and Brugia malayi adult female worms in vivo.
J Biomed Sci. 2012 Feb 9 ;19(1):21.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: