Exp Cell Res. 1985 Jan;156(1):1-6.

Cell growth, cell division and cell size homeostasis in Swiss 3T3 cells.

Abstract

By separating large and small 3T3 cells we show here that cell growth (in volume) after stimulation from quiescence is not 'autocatalytic'. Rather, large cells grow significantly more slowly, in relative terms, than small cells. It follows that 3T3 cells do not require a size control mechanism operating at the level of division timing in order to achieve cell size homeostasis.

PMID:: 3965288; [PubMed - indexed for MEDLINE]

MeSH Terms

LinkOut - more resources

Full Text Sources

Elsevier Science

Libraries

LinkOut Holdings

Supplemental Content

Related citations

Daidzein inhibits insulin- or insulin-like growth factor-1-mediated signaling in cell cycle progression of Swiss 3T3 cells. [Biochim Biophys Acta. 1994]
Daidzein inhibits insulin- or insulin-like growth factor-1-mediated signaling in cell cycle progression of Swiss 3T3 cells.
Higashi K, Ogawara H. Biochim Biophys Acta. 1994 Mar 10; 1221(1):29-35.
A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts. [J Biol Chem. 1997]
A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts.
Vaziri C, Faller DV. J Biol Chem. 1997 Jan 31; 272(5):2762-9.
Control of division by cell contact and serum concentration in cultures of 3T3 cells. [Exp Cell Res. 1971]
Control of division by cell contact and serum concentration in cultures of 3T3 cells.
Castor LN. Exp Cell Res. 1971 Sep; 68(1):17-24.
Review A cell culture model for the study of epidermal (chalone) homeostasis. [Pharmacol Ther. 1980]
Review A cell culture model for the study of epidermal (chalone) homeostasis.
Prunieras M, Delescluse C, Regnier M. Pharmacol Ther. 1980; 9(3):271-95.
Review The flexible evolutionary anchorage-dependent Pardee's restriction point of mammalian cells: how its deregulation may lead to cancer. [Biochim Biophys Acta. 2006]
Review The flexible evolutionary anchorage-dependent Pardee's restriction point of mammalian cells: how its deregulation may lead to cancer.
David-Pfeuty T. Biochim Biophys Acta. 2006 Jan; 1765(1):38-66. Epub 2005 Sep 20.

See reviews... See all...

Cited by 3 PubMed Central articles

Measurement of adherent cell mass and growth. [Proc Natl Acad Sci U S A. 2010]
Measurement of adherent cell mass and growth.
Park K, Millet LJ, Kim N, Li H, Jin X, Popescu G, Aluru NR, Hsia KJ, Bashir R. Proc Natl Acad Sci U S A. 2010 Nov 30; 107(48):20691-6. Epub 2010 Nov 10.
Differences in the way a mammalian cell and yeast cells coordinate cell growth and cell-cycle progression. [J Biol. 2003]
Differences in the way a mammalian cell and yeast cells coordinate cell growth and cell-cycle progression.
Conlon I, Raff M. J Biol. 2003; 2(1):7. Epub 2003 Apr 24.
Review Does size matter? [J Cell Biol. 2002]
Review Does size matter?
Wells WA. J Cell Biol. 2002 Sep 30; 158(7):1156-9.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Cell growth, cell division and cell size homeostasis in Swiss 3T3 cells.
Cell growth, cell division and cell size homeostasis in Swiss 3T3 cells.
Exp Cell Res. 1985 Jan ;156(1):1-6.

PubMed
Suppression of cytoplasmic protein uptake by lysosomes as the mechanism of prote...
Suppression of cytoplasmic protein uptake by lysosomes as the mechanism of protein regain in livers of starved-refed mice.
J Biol Chem. 1982 Aug 25 ;257(16):9548-54.

PubMed
Characterization and cloning of a Dictyostelium Ste20-like protein kinase that p...
Characterization and cloning of a Dictyostelium Ste20-like protein kinase that phosphorylates the actin-binding protein severin.
J Biol Chem. 1998 May 22 ;273(21):12952-9.

PubMed
Size control in animal development.
Size control in animal development.
Cell. 1999 Jan 22 ;96(2):235-44.

PubMed
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, p...
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate.
J Biol Chem. 1998 May 29 ;273(22):13375-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

Cell growth, cell division and cell size homeostasis in Swiss 3T3 cells.

Abstract

MeSH Terms

MeSH Terms

LinkOut - more resources

Full Text Sources

Libraries

Supplemental Content

Related citations

Cited by 3 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information