Neurology. 1985 Mar;35(3):300-6.

Neurologic complications of bone marrow transplantation.

Patchell RA, White CL 3rd, Clark AW, Beschorner WE, Santos GW.

Abstract

Among 78 patients who died after bone marrow transplantation, neurologic complications were present in 55 (70%) and were the cause of death in 5 (6%). Metabolic encephalopathy occurred in 29 patients (37%). CNS infections included aspergillosis (3), herpes simplex encephalitis (2), and Listeria monocytogenes meningitis (1). Six additional patients had neuropathologic changes possibly due to cytomegalovirus infection. Cerebrovascular complications occurred in five patients (two hemorrhages and three infarcts). All infarcts were associated with endocarditis. The rate of nonbacterial thrombotic endocarditis was significantly higher (p less than 0.001) than in the general autopsy population. CNS leukemia and therapy-induced injury were rare. There was no evidence of graft-versus-host disease involving the CNS.

PMID:: 3883233; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

Neurologic complications of autologous and allogeneic bone marrow transplantation in patients with leukemia: a comparative study. [Neurology. 1996]
Neurologic complications of autologous and allogeneic bone marrow transplantation in patients with leukemia: a comparative study.
Graus F, Saiz A, Sierra J, Arbaiza D, Rovira M, Carreras E, Tolosa E, Rozman C. Neurology. 1996 Apr; 46(4):1004-9.
Early central nervous system complications after reduced-intensity stem cell transplantation. [Biol Blood Marrow Transplant. ...]
Early central nervous system complications after reduced-intensity stem cell transplantation.
Kishi Y, Miyakoshi S, Kami M, Ikeda M, Katayama Y, Murashige N, Kusumi E, Yuji K, Kobayashi K, Kato D, et al. Biol Blood Marrow Transplant. 2004 Aug; 10(8):561-8.
Neuropathological findings after bone marrow transplantation: an autopsy study of 180 cases. [Bone Marrow Transplant. 2000]
Neuropathological findings after bone marrow transplantation: an autopsy study of 180 cases.
Bleggi-Torres LF, de Medeiros BC, Werner B, Neto JZ, Loddo G, Pasquini R, de Medeiros CR. Bone Marrow Transplant. 2000 Feb; 25(3):301-7.
Review Neurologic complications of bone marrow transplantation. [Neurol Clin. 1988]
Review Neurologic complications of bone marrow transplantation.
Davis DG, Patchell RA. Neurol Clin. 1988 May; 6(2):377-87.
Review Neurologic complications of liver transplantation. [Neurol Clin. 1988]
Review Neurologic complications of liver transplantation.
Martinez AJ, Estol C, Faris AA. Neurol Clin. 1988 May; 6(2):327-48.

See reviews... See all...

Cited by 3 PubMed Central articles

Review Human malarial disease: a consequence of inflammatory cytokine release. [Malar J. 2006]
Review Human malarial disease: a consequence of inflammatory cytokine release.
Clark IA, Budd AC, Alleva LM, Cowden WB. Malar J. 2006 Oct 10; 5:85. Epub 2006 Oct 10.
Increased incidence of neurological complications in patients receiving an allogenic bone marrow transplantation from alternative donors. [J Neurol Neurosurg Psychiatry....]
Increased incidence of neurological complications in patients receiving an allogenic bone marrow transplantation from alternative donors.
de Brabander C, Cornelissen J, Smitt PA, Vecht CJ, van den Bent MJ. J Neurol Neurosurg Psychiatry. 2000 Jan; 68(1):36-40.
Multiple sclerosis in the north Cambridgeshire districts of East Anglia. [J Neurol Neurosurg Psychiatry....]
Multiple sclerosis in the north Cambridgeshire districts of East Anglia.
Robertson N, Deans J, Fraser M, Compston DA. J Neurol Neurosurg Psychiatry. 1995 Jul; 59(1):71-6.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Neurologic complications of bone marrow transplantation.
Neurologic complications of bone marrow transplantation.
Neurology. 1985 Mar ;35(3):300-6.

PubMed
Experimental malaria in the CBA/N mouse.
Experimental malaria in the CBA/N mouse.
J Immunol. 1979 Dec ;123(6):2532-9.

PubMed
The role of voluntary village aides in the control of malaria by presumptive tre...
The role of voluntary village aides in the control of malaria by presumptive treatment of fever. 2. Impact on village health.
P N G Med J. 1985 Dec ;28(4):267-78.

PubMed
Synchronization of Plasmodium falciparum erythrocytic stages in culture.
Synchronization of Plasmodium falciparum erythrocytic stages in culture.
J Parasitol. 1979 Jun ;65(3):418-20.

PubMed
[Arbovirus-vector relations].
[Arbovirus-vector relations].
Bull Soc Pathol Exot Filiales. 1985 ;78(5 Pt 2):763-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Neurologic complications of bone marrow transplantation.

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Medical

Molecular Biology Databases

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 3 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information