GERD as a Complication of Laparoscopic Sleeve Gastrectomy for the Treatment of Obesity: A Systematic Review and Meta-Analysis

Przemysław Znamirowski; Magdalena Kołomańska; Robert Mazurkiewicz; Oksana Tymchyshyn; Łukasz Nawacki

doi:10.3390/jpm13081243

GERD as a Complication of Laparoscopic Sleeve Gastrectomy for the Treatment of Obesity: A Systematic Review and Meta-Analysis

J Pers Med. 2023 Aug 10;13(8):1243. doi: 10.3390/jpm13081243.

Authors

Przemysław Znamirowski¹, Magdalena Kołomańska¹, Robert Mazurkiewicz¹, Oksana Tymchyshyn¹, Łukasz Nawacki¹

Affiliation

¹ Collegium Medicum, The Jan Kochanowski University, 25-369 Kielce, Poland.

Abstract

Introduction: The incidence of obesity is increasing in developed societies, and surgical treatment is one treatment option. The most common surgical treatment for obesity is laparoscopic sleeve gastrectomy (LSG). Gastroesophageal reflux disease (GERD) is a complication of both obesity and the surgical treatment of obesity.

Materials and methods: In this study, the PubMed database was searched using the keywords "GERD" and "bariatric surgery", and 987 papers published between 1 July 2017 and 30 June 2022 were retrieved.

Results: Nine papers met the inclusion criteria and were included in the meta-analysis. The articles were analyzed for the de novo occurrence of GERD after the treatment of its symptoms, the occurrence of erosive esophagitis, and Barrett's esophagus. In addition, interesting conclusions are presented from the papers that did not meet the inclusion criteria but shed light on the pathophysiology of GERD in obese patients undergoing LSG.

Conclusion: In conclusion, the authors draw attention to the need for endoscopic surveillance in patients undergoing LSG, even in the absence of clinical signs of GERD.

Keywords: Barrett’s esophagus; GERD; LSG; bariatric surgery; erosive esophagitis; esophageal adenocarcinoma.

Publication types

Review

Grants and funding

The project was financed under the program the Minister of Education and Science called “Regional Initiative of Excellence” in the years 2019–2023, project no. 024/RID/2018/19, amount of financing 11,999,000,00 PLN.