Chest. 1978 Feb;73(2):173-8.

The management of acute quinidine intoxication.

Shub C, Gau GT, Sidell PM, Brennan LA Jr.

Abstract

A 16-year-old patient survived severe intoxication with quinidine. Hypotension, rapidly progressing to oliguria and shock, was resistant to the usual therapeutic interventions but responded favorably to the use of an intra-aortic balloon pump. Some hemodynamic implications are discussed. Pulmonary edema occurred and was treated with positive end-expiratory pressure. Electrocardiographic disturbances in conduction, transient bradycardia and recurrent ventricular arrhythmias characterized the initial 36-hour critical period. Unexplained electrolyte abnormalities occurred and further complicated management.

PMID:: 340161; [PubMed - indexed for MEDLINE]

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The management of acute quinidine intoxication.

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