J Lab Clin Med. 1978 Nov;92(5):822-8.

Failure to respond to influenza vaccine in the aged: correlation with B-cell number and function.

Phair J, Kauffman CA, Bjornson A, Adams L, Linnemann C Jr.

Abstract

Failure to respond to influenza vaccination correlated with a decreased number and percentage of IgD-bearing PBL and a dampened lymphocyte response to PWM in a subset of healthy aged volunteers. These subjects had normal levels of serum immunoglobulins, intact T cell function, and normal numbers of E-rosetting cells.

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