AIEgen-Based Fluorescent Nanomaterials: Fabrication and Biological Applications

Molecules. 2018 Feb 14;23(2):419. doi: 10.3390/molecules23020419.

Abstract

In recent years, luminogens with the feature of aggregation-induced emission (AIEgen) have emerged as advanced luminescent materials for fluorescent nanomaterial preparation. AIEgen-based nanomaterials show enhanced fluorescence efficiency and superior photostability, which thusly offer unique advantages in biological applications. In this review, we will summarize the fabrication methods of AIEgen-based nanomaterials and their applications in in vitro/in vivo imaging, cell tracing, photodynamic therapy and drug delivery, focusing on the recent progress.

Keywords: AIE; bioimaging; cell tracing; fluorescent nanomaterials; theranosis.

Publication types

  • Review

MeSH terms

  • Fluorescence
  • Fluorescent Dyes / chemistry
  • Humans
  • Luminescence*
  • Luminescent Agents / chemistry*
  • Nanoparticles / chemistry*
  • Nanostructures / chemistry*

Substances

  • Fluorescent Dyes
  • Luminescent Agents