Nitrogen-Doped Diamond Film for Optical Investigation of Hemoglobin Concentration

Daria Majchrowicz; Monika Kosowska; Kamatchi J Sankaran; Przemysław Struk; Michał Wąsowicz; Michał Sobaszek; Ken Haenen; Małgorzata Jędrzejewska-Szczerska

doi:10.3390/ma11010109

Nitrogen-Doped Diamond Film for Optical Investigation of Hemoglobin Concentration

Materials (Basel). 2018 Jan 11;11(1):109. doi: 10.3390/ma11010109.

Authors

Daria Majchrowicz¹, Monika Kosowska², Kamatchi J Sankaran^{3

4}, Przemysław Struk⁵, Michał Wąsowicz⁶, Michał Sobaszek⁷, Ken Haenen^{8

9}, Małgorzata Jędrzejewska-Szczerska¹⁰

Affiliations

¹ Department of Metrology and Optoelectronics, Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, 80-233 Gdansk, Poland. majchrowiczdaria@gmail.com.
² Department of Metrology and Optoelectronics, Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, 80-233 Gdansk, Poland. nika.kosowska@gmail.com.
³ Institute for Materials Research (IMO), Hasselt University, B-3590 Diepenbeek, Belgium. sankaran.kamatchi@uhasselt.be.
⁴ IMOMEC, IMEC vzw, B-3590 Diepenbeek, Belgium. sankaran.kamatchi@uhasselt.be.
⁵ Department of Optoelectronics, Faculty of Electrical Engineering, Silesian University of Technology, 44-100 Gliwice, Poland. przemyslaw.struk@polsl.pl.
⁶ Department of Morphological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, 02-776 Warszawa, Poland. wasowiczm@gmail.com.
⁷ Department of Metrology and Optoelectronics, Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, 80-233 Gdansk, Poland. micsobas@pg.gda.pl.
⁸ Institute for Materials Research (IMO), Hasselt University, B-3590 Diepenbeek, Belgium. ken.haenen@uhasselt.be.
⁹ IMOMEC, IMEC vzw, B-3590 Diepenbeek, Belgium. ken.haenen@uhasselt.be.
¹⁰ Department of Metrology and Optoelectronics, Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology, 80-233 Gdansk, Poland. mjedrzej@eti.pg.edu.pl.

Abstract

In this work we present the fabrication and characterization of a diamond film which can be utilized in the construction of optical sensors for the investigation of biological samples. We produced a nitrogen-doped diamond (NDD) film using a microwave plasma enhanced chemical vapor deposition (MWPECVD) system. The NDD film was investigated with the use of scanning electron microscopy (SEM), atomic force microscopy (AFM) and Raman spectroscopy. The NDD film was used in the construction of the fiber optic sensor. This sensor is based on the Fabry-Pérot interferometer working in a reflective mode and the NDD film is utilized as a reflective layer of this interferometer. Application of the NDD film allowed us to obtain the sensor of hemoglobin concentration with linear work characteristics with a correlation coefficient (R²) equal to 0.988.

Keywords: Fabry–Pérot sensor; biophotnic sensor; fiber optic sensor; hemoglobin; interferometer; nitrogen-doped diamond.