Inflammatory bowel disease and airway diseases

World J Gastroenterol. 2016 Sep 14;22(34):7735-41. doi: 10.3748/wjg.v22.i34.7735.

Abstract

Airway diseases are the most commonly described lung manifestations of inflammatory bowel disease (IBD). However, the similarities in disease pathogenesis and the sharing of important environmental risk factors and genetic susceptibility suggest that there is a complex interplay between IBD and airway diseases. Recent evidence of IBD occurrence among patients with airway diseases and the higher than estimated prevalence of subclinical airway injuries among IBD patients support the hypothesis of a two-way association. Future research efforts should be directed toward further exploration of this association, as airway diseases are highly prevalent conditions with a substantial public health impact.

Keywords: Asthma; Chronic obstructive pulmonary disease; Crohn's disease; Inflammatory bowel disease; Ulcerative colitis.

Publication types

  • Review

MeSH terms

  • Animals
  • Asthma / complications
  • Colitis, Ulcerative / complications*
  • Crohn Disease / complications*
  • Environment
  • Genetic Predisposition to Disease
  • Humans
  • Inflammation
  • Inflammatory Bowel Diseases / complications*
  • Lung / physiopathology
  • Prevalence
  • Prognosis
  • Pulmonary Disease, Chronic Obstructive / complications
  • Respiration Disorders / complications*
  • Risk Factors