Acta Cytol. 1990 Nov-Dec;34(6):767-70.

Fine needle aspiration cytologic findings in a case of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman syndrome).

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Department of Pathology, University of California, Los Angeles.

Abstract

The clinical, fine needle aspiration (FNA) cytologic and histologic findings in a case of sinus histiocytosis with massive lymphadenopathy (SHML) in a five-year-old boy are presented. The FNA smears showed a proliferation of plasma cells, lymphoid cells and histiocytes demonstrating emperipolesis that is characteristic of this benign disorder; these cytologic findings were reported as a reactive lymphoid infiltrate with a high content of benign histiocytes. The diagnosis was made on a subsequent open biopsy performed on the persistent lymphadenopathy. The differential diagnosis of lymph nodes containing a prominent component of histiocytes is discussed.

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Review Fine needle aspiration cytology and immunocytochemical characterization of the histiocytes in sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman syndrome). [Acta Cytol. 1990]
Review Fine needle aspiration cytology and immunocytochemical characterization of the histiocytes in sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman syndrome).
Pettinato G, Manivel JC, d'Amore ES, Petrella G. Acta Cytol. 1990 Nov-Dec; 34(6):771-7.
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Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): diagnosis with fine-needle aspiration in a case with nodal and nasal involvement. [Diagn Cytopathol. 1995]
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Review Primary Rosai-Dorfman disease of bone without lymphadenopathy diagnosed by fine needle aspiration cytology. A case report. [Acta Cytol. 2003]
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Goel MM, Agarwal PK, Agarwal S. Acta Cytol. 2003 Nov-Dec; 47(6):1119-22.

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Cited by 2 PubMed Central articles

Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease): A case report and review of 49 cases with fine needle aspiration cytology. [Cytojournal. 2011]
Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease): A case report and review of 49 cases with fine needle aspiration cytology.
Shi Y, Griffin AC, Zhang PJ, Palmer JN, Gupta P. Cytojournal. 2011 Feb 12; 8:3. Epub 2011 Feb 12.
Rosai dorfman disease of the orbit. [J Hematol Oncol. 2008]
Rosai dorfman disease of the orbit.
Vemuganti GK, Naik MN, Honavar SG. J Hematol Oncol. 2008 Jun 28; 1:7. Epub 2008 Jun 28.

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