Br J Cancer. 1990 Sep;62(3):451-3.

Serum oestrogen levels in postmenopausal women: comparison of American whites and Japanese in Japan.

Shimizu H, Ross RK, Bernstein L, Pike MC, Henderson BE.

Source

Department of Public Health, Gifu University School of Medicine, Japan.

Abstract

Serum oestrone (E1), oestradiol (E2) and sex hormone binding globulin (SHBG) levels were studied in postmenopausal Japanese women in Japan (n = 91) and postmenopausal American white women (n = 38). The Japanese women were deliberately chosen to be from a rural agricultural area in order to get samples which represent as closely as possible the traditional Japanese 'lifestyle' that gave rise to the low rates of breast cancer in Japan. E1 levels were 47%, and E2 levels 36%, greater in the American women; these differences were only reduced to 43% and 27% after adjustment for the lower weight of the Japanese. These results were all statistically highly significant. There was little difference in SHBG levels between the Japanese and the American women. These results for E1 and E2 could be an important part of the explanation why Japanese and American breast cancer rates continue to diverge further after the menopause.

PMID:: 2206953; [PubMed - indexed for MEDLINE]
PMCID:: PMC1971457

Free PMC Article

LinkOut - more resources

Full Text Sources

Medical

Menopause - MedlinePlus Health Information

Molecular Biology Databases

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Ethnic differences in post-menopausal plasma oestrogen levels: high oestrone levels in Japanese-American women despite low weight. [Br J Cancer. 2000]
Ethnic differences in post-menopausal plasma oestrogen levels: high oestrone levels in Japanese-American women despite low weight.
Probst-Hensch NM, Pike MC, McKean-Cowdin R, Stanczyk FZ, Kolonel LN, Henderson BE. Br J Cancer. 2000 Jun; 82(11):1867-70.
The relationship between endogenous estrogen, sex hormone-binding globulin, and bone loss in female residents of a rural Japanese community: the Taiji Study. [J Bone Miner Metab. 2002]
The relationship between endogenous estrogen, sex hormone-binding globulin, and bone loss in female residents of a rural Japanese community: the Taiji Study.
Yoshimura N, Kasamatsu T, Sakata K, Hashimoto T, Cooper C. J Bone Miner Metab. 2002; 20(5):303-10.
Racial/ethnic differences in postmenopausal endogenous hormones: the multiethnic cohort study. [Cancer Epidemiol Biomarkers Pr...]
Racial/ethnic differences in postmenopausal endogenous hormones: the multiethnic cohort study.
Setiawan VW, Haiman CA, Stanczyk FZ, Le Marchand L, Henderson BE. Cancer Epidemiol Biomarkers Prev. 2006 Oct; 15(10):1849-55.
Effects of the aromatase inhibitor anastrozole on serum oestrogens in Japanese and Caucasian women. [Cancer Chemother Pharmacol. 2000]
Effects of the aromatase inhibitor anastrozole on serum oestrogens in Japanese and Caucasian women.
Dowsett M, Donaldson K, Tsuboi M, Wong J, Yates R. Cancer Chemother Pharmacol. 2000; 46(1):35-9.
Hormone levels during dietary changes in premenopausal African-American women. [J Natl Cancer Inst. 1996]
Hormone levels during dietary changes in premenopausal African-American women.
Woods MN, Barnett JB, Spiegelman D, Trail N, Hertzmark E, Longcope C, Gorbach SL. J Natl Cancer Inst. 1996 Oct 2; 88(19):1369-74.

See reviews... See all...

Cited by 9 PubMed Central articles

Polymorphisms in steroidogenesis genes, sex steroid levels, and high myopia in the Taiwanese population. [Mol Vis. 2011]
Polymorphisms in steroidogenesis genes, sex steroid levels, and high myopia in the Taiwanese population.
Chen ZT, Wang IJ, Liao YT, Shih YF, Lin LL. Mol Vis. 2011; 17:2297-310. Epub 2011 Aug 25.
Plasma sex hormone concentrations and breast cancer risk in an ethnically diverse population of postmenopausal women: the Multiethnic Cohort Study. [Endocr Relat Cancer. 2010]
Plasma sex hormone concentrations and breast cancer risk in an ethnically diverse population of postmenopausal women: the Multiethnic Cohort Study.
Woolcott CG, Shvetsov YB, Stanczyk FZ, Wilkens LR, White KK, Caberto C, Henderson BE, Le Marchand L, Kolonel LN, Goodman MT. Endocr Relat Cancer. 2010 Mar; 17(1):125-34. Epub 2010 Feb 18.
Factors related to declining luteal function in women during the menopausal transition. [J Clin Endocrinol Metab. 2008]
Factors related to declining luteal function in women during the menopausal transition.
Santoro N, Crawford SL, Lasley WL, Luborsky JL, Matthews KA, McConnell D, Randolph JF Jr, Gold EB, Greendale GA, Korenman SG, et al. J Clin Endocrinol Metab. 2008 May; 93(5):1711-21. Epub 2008 Feb 19.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Serum oestrogen levels in postmenopausal women: comparison of American whites an...
Serum oestrogen levels in postmenopausal women: comparison of American whites and Japanese in Japan.
Br J Cancer. 1990 Sep ;62(3):451-3.

PubMed
Structural, stability, dynamic and binding properties of the ALS-causing T46I mu...
Structural, stability, dynamic and binding properties of the ALS-causing T46I mutant of the hVAPB MSP domain as revealed by NMR and MD simulations.
PLoS One. 2011 ;6(11):e27072. Epub 2011 Nov 1 .

PubMed
Systematic trends across the night in human sleep cycles.
Systematic trends across the night in human sleep cycles.
Psychophysiology. 1979 May ;16(3):283-91.

PubMed
The spontaneous regression of cancer. A review of cases from 1900 to 1987.
The spontaneous regression of cancer. A review of cases from 1900 to 1987.
Acta Oncol. 1990 ;29(5):545-50.

PubMed
Pandemic A/H1N1v influenza 2009 in hospitalized children: a multicenter Belgian ...
Pandemic A/H1N1v influenza 2009 in hospitalized children: a multicenter Belgian survey.
BMC Infect Dis. 2011 Nov 7 ;11:313.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Serum oestrogen levels in postmenopausal women: comparison of American whites and Japanese in Japan.

Source

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Medical

Molecular Biology Databases

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 9 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information