Biochim Biophys Acta. 1990 Jul 20;1035(1):113-6.

Serum esterase activities and hyperlipidaemia in the streptozotocin-diabetic rat.

Patel BN, Mackness MI, Harty DW, Arrol S, Boot-Handford RP, Durrington PN.

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Department of Biochemistry and Molecular Biology, University of Manchester Medical School, U.K.

Abstract

The levels of activity of four serum esterases were measured in control and streptozotocin-diabetic rats for a period of 6 months. Pseudocholinesterase activity was significantly elevated in the diabetic rats at all time points tested, reaching 250% of the control activity at 6 months. Levels of paraoxonase activity progressively decreased with time in the diabetic rats, being 36% lower than in controls at 6 months. No significant differences in either serum arylesterase or carboxylesterase activity between control and diabetic rats were observed.

PMID:: 2143419; [PubMed - indexed for MEDLINE]

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