Display Settings:

Format

Send to:

Choose Destination
    J Virol. 1990 Jun;64(6):3097-9.

    Human immunodeficiency virus vpr product is a virion-associated regulatory protein.

    Source

    Division of Human Retrovirology, Dana-Farber Cancer Institute, Boston, Massachusetts.

    Abstract

    The vpr product of the human immunodeficiency virus type 1 (HIV-1) acts in trans to accelerate virus replication and cytopathic effect in T cells. Here it is shown that the HIV-1 viral particle contains multiple copies of the vpr protein. The vpr product is the first regulatory protein of HIV-1 to be found in the virus particle. This observation raises the possibility that vpr acts to facilitate the early steps of infection before de novo viral protein synthesis occurs.

    PMID:
    2139896
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC249501
    Free PMC Article

      Supplemental Content

      Icon for HighWire Press Icon for PubMed Central

      Save items

      loading

      Recent activity

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      Write to the Help Desk