Trends Genet. 1990 Apr;6(4):121-5.

Metalloproteinases and their inhibitors in matrix remodeling.

Source

Department of Cell Biology, School of Medicine, Vanderbilt University, Nashville, TN 37232.

Abstract

The matrix metalloproteinases are a tightly regulated family of enzymes that degrade extracellular matrix and basement membrane components. Recent evidence suggests that these proteases and their specific inhibitors play important roles in normal developmental processes and in pathological conditions. Interestingly, experiments designed to improve our understanding of metalloproteinase regulation have also resulted in new insights into mechanisms by which growth factors and proto-oncogenes may regulate biological processes.

PMID:: 2132731; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Review Matrix metalloproteinases: a review. [Crit Rev Oral Biol Med. 1993]
Review Matrix metalloproteinases: a review.
Birkedal-Hansen H, Moore WG, Bodden MK, Windsor LJ, Birkedal-Hansen B, DeCarlo A, Engler JA. Crit Rev Oral Biol Med. 1993; 4(2):197-250.
Review Matrix degrading metalloproteinases. [J Neurooncol. 1994]
Review Matrix degrading metalloproteinases.
Ennis BW, Matrisian LM. J Neurooncol. 1994; 18(2):105-9.
Review The matrix-degrading metalloproteinases. [Bioessays. 1992]
Review The matrix-degrading metalloproteinases.
Matrisian LM. Bioessays. 1992 Jul; 14(7):455-63.
Review The matrix metalloproteinases and their inhibitors. [Am J Respir Cell Mol Biol. 1992]
Review The matrix metalloproteinases and their inhibitors.
Murphy G, Docherty AJ. Am J Respir Cell Mol Biol. 1992 Aug; 7(2):120-5.
Review Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease. [Biol Chem Hoppe Seyler. 1995]
Review Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease.
Ries C, Petrides PE. Biol Chem Hoppe Seyler. 1995 Jun; 376(6):345-55.

See reviews... See all...

Cited by over 100 PubMed Central articles

Biomarkers for identifying the early phases of osteoarthritis secondary to medial patellar luxation in dogs. [J Vet Sci. 2011]
Biomarkers for identifying the early phases of osteoarthritis secondary to medial patellar luxation in dogs.
Alam MR, Ji JR, Kim MS, Kim NS. J Vet Sci. 2011 Sep; 12(3):273-80.
Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer. [World J Gastroenterol. 2011]
Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer.
Kemik O, Kemik AS, Sümer A, Dulger AC, Adas M, Begenik H, Hasirci I, Yilmaz O, Purisa S, Kisli E, et al. World J Gastroenterol. 2011 Apr 28; 17(16):2109-12.
Spotlight on differentially expressed genes in urinary bladder cancer. [PLoS One. 2011]
Spotlight on differentially expressed genes in urinary bladder cancer.
Zaravinos A, Lambrou GI, Volanis D, Delakas D, Spandidos DA. PLoS One. 2011 Apr 5; 6(4):e18255. Epub 2011 Apr 5.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Gene (OMIM)
Gene records associated with Online Mendelian Inheritance in Man (OMIM) records that cite the current articles in their reference lists.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
OMIM (cited)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as reference cited at the end of the OMIM record.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Metalloproteinases and their inhibitors in matrix remodeling.
Metalloproteinases and their inhibitors in matrix remodeling.
Trends Genet. 1990 Apr ;6(4):121-5.

PubMed
The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is me...
The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression.
Breast Cancer Res. 2011 Feb 9 ;13(1):R19.

PubMed
Mutation in a heterochromatin-specific chromosomal protein is associated with su...
Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.
Proc Natl Acad Sci U S A. 1990 Dec ;87(24):9923-7.

PubMed
Mammographic density and its interaction with other breast cancer risk factors i...
Mammographic density and its interaction with other breast cancer risk factors in an Asian population.
Br J Cancer. 2011 Mar 1 ;104(5):871-4. Epub 2011 Jan 18 .

PubMed
Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun c...
Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex.
Cell. 1990 Dec 21 ;63(6):1267-76.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Metalloproteinases and their inhibitors in matrix remodeling.

Source

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by over 100 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information