Infect Immun. 1990 Jan;58(1):254-6.

Comparative protection of mice against virulent and attenuated strains of Brucella abortus by passive transfer of immune T cells or serum.

Source

Department of Veterinary Microbiology, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.

Abstract

Passively transferred immune serum provided significantly greater protection to BALB/c mice against attenuated Brucella abortus 19 than against virulent strain 2308, whether serum donors had been infected with strain 19 or 2308. In contrast, immune T cells conferred better protection upon recipients challenged with the homologous strain of B. abortus. It is hypothesized that strain 2308, but not strain 19, can survive in macrophages after opsonization and that epitopes which induce protective cell-mediated immunity may differ between strains 19 and 2308.

PMID:: 2104599; [PubMed - indexed for MEDLINE]
PMCID:: PMC258438

Free PMC Article

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH Terms

Substances

Antibodies, Bacterial

LinkOut - more resources

Full Text Sources

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Antibody-mediated protection against Brucella abortus in BALB/c mice at successive periods after infection: variation between virulent strain 2308 and attenuated vaccine strain 19. [Immunology. 1994]
Antibody-mediated protection against Brucella abortus in BALB/c mice at successive periods after infection: variation between virulent strain 2308 and attenuated vaccine strain 19.
Elzer PH, Jacobson RH, Jones SM, Nielsen KH, Douglas JT, Winter AJ. Immunology. 1994 Aug; 82(4):651-8.
Temporal development of protective cell-mediated and humoral immunity in BALB/c mice infected with Brucella abortus. [J Immunol. 1989]
Temporal development of protective cell-mediated and humoral immunity in BALB/c mice infected with Brucella abortus.
Araya LN, Elzer PH, Rowe GE, Enright FM, Winter AJ. J Immunol. 1989 Nov 15; 143(10):3330-7.
Vaccination with Brucella abortus rough mutant RB51 protects BALB/c mice against virulent strains of Brucella abortus, Brucella melitensis, and Brucella ovis. [Infect Immun. 1994]
Vaccination with Brucella abortus rough mutant RB51 protects BALB/c mice against virulent strains of Brucella abortus, Brucella melitensis, and Brucella ovis.
Jiménez de Bagüés MP, Elzer PH, Jones SM, Blasco JM, Enright FM, Schurig GG, Winter AJ. Infect Immun. 1994 Nov; 62(11):4990-6.
Review Macrophages and Brucella. [Immunol Ser. 1994]
Review Macrophages and Brucella.
Baldwin CL, Winter AJ. Immunol Ser. 1994; 60:363-80.
Review [Pathogenesis of brucellosis]. [Pol Arch Med Wewn. 1983]
Review [Pathogenesis of brucellosis].
Juszczyk J. Pol Arch Med Wewn. 1983 Jul-Aug; 70(1-2):43-53.

See reviews... See all...

Cited by 23 PubMed Central articles

Liposomal delivery of p-ialB and p-omp25 DNA vaccines improves immunogenicity but fails to provide full protection against B. melitensis challenge. [Genet Vaccines Ther. 2010]
Liposomal delivery of p-ialB and p-omp25 DNA vaccines improves immunogenicity but fails to provide full protection against B. melitensis challenge.
Commander NJ, Brewer JM, Wren BW, Spencer SA, Macmillan AP, Stack JA. Genet Vaccines Ther. 2010 Jul 16; 8:5. Epub 2010 Jul 16.
Human brucellosis is characterized by an intense Th1 profile associated with a defective monocyte function. [Infect Immun. 2010]
Human brucellosis is characterized by an intense Th1 profile associated with a defective monocyte function.
Rodríguez-Zapata M, Matías MJ, Prieto A, Jonde MA, Monserrat J, Sánchez L, Reyes E, De la Hera A, Alvarez-Mon M. Infect Immun. 2010 Jul; 78(7):3272-9. Epub 2010 Apr 19.
A B lymphocyte mitogen is a Brucella abortus virulence factor required for persistent infection. [Proc Natl Acad Sci U S A. 2006]
A B lymphocyte mitogen is a Brucella abortus virulence factor required for persistent infection.
Spera JM, Ugalde JE, Mucci J, Comerci DJ, Ugalde RA. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16514-9. Epub 2006 Oct 19.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Comparative protection of mice against virulent and attenuated strains of Brucel...
Comparative protection of mice against virulent and attenuated strains of Brucella abortus by passive transfer of immune T cells or serum.
Infect Immun. 1990 Jan ;58(1):254-6.

PubMed
A strategy of tumor treatment in mice with doxorubicin-cyclophosphamide combinat...
A strategy of tumor treatment in mice with doxorubicin-cyclophosphamide combination based on dendritic cell activation by human double-stranded DNA preparation.
Genet Vaccines Ther. 2010 Nov 1 ;8:7.

PubMed
Exploring the molecular basis for variability among patients with Becker muscula...
Exploring the molecular basis for variability among patients with Becker muscular dystrophy: dystrophin gene and protein studies.
Am J Hum Genet. 1991 Jul ;49(1):54-67.

PubMed
Liposomal delivery of p-ialB and p-omp25 DNA vaccines improves immunogenicity bu...
Liposomal delivery of p-ialB and p-omp25 DNA vaccines improves immunogenicity but fails to provide full protection against B. melitensis challenge.
Genet Vaccines Ther. 2010 Jul 16 ;8:5.

PubMed
Selection of splice sites in pre-mRNAs with short internal exons.
Selection of splice sites in pre-mRNAs with short internal exons.
Mol Cell Biol. 1991 Dec ;11(12):6075-83.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: