Science. 1977 Oct 28;198(4315):423-5.

Memory formation: evidence for a specific neurochemical system in the amygdala.

Gallagher M, Kapp BS, Musty RE, Driscoll PA.

Abstract

beta-Adrenergic antagonists injected into the amygdala complex of rats trained in a passive avoidance task produced time-dependent and dose-dependent decreases in retention of the task. In addition, the effects observed with beta-adrenergic antagonists were both stereospecific and reversed by norepinephrine. The results support a role for an amygdala beta-adrenergic system in memory processes.

PMID:: 20664; [PubMed - indexed for MEDLINE]

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Research Support, U.S. Gov't, Non-P.H.S.

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Adrenergic beta-Antagonists

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