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    Trends Parasitol. 2010 Aug;26(8):373-5. Epub 2010 Jun 16.

    Wolbachia pipientis: an expanding bag of tricks to explore for disease control.

    Source

    School of Biological Sciences, The University of Queensland, Brisbane, Australia.

    Abstract

    Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects. Two recent studies have demonstrated that Wolbachia inhibits the ability of medically significant pathogens, including filarial nematodes, dengue virus and Plasmodium to form infections in the mosquito vector, Aedes aegypti. We highlight the added value of these traits for Wolbachia based biocontrol strategies and evaluate the evidence for the idea that the insect immune response is responsible for the pathogen inhibition.

    Copyright 2010 Elsevier Ltd. All rights reserved.

    PMID:
    20647151
    [PubMed - indexed for MEDLINE]

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