Warning: The NCBI web site requires JavaScript to function. more...
Generate a file for use with external citation management software.
Dept of Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Clonal deletion and anergy are believed by many immunologists to be the fundamental mechanisms responsible for self tolerance. Nevertheless, as Irun Cohen and Douglas Young point out, such notions of nonreactivity cannot explain certain key features of immune behaviour: the immunological dominance of microbial antigens that mimic self, the uniformity of autoimmune diseases and the prevalence of natural autoimmunity among the healthy. The theory of the immunological homunculus is presented here as a unifying principle.
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on