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    Chem Phys Lipids. 1991 Mar;57(2-3):213-26.

    Phospholipid phase transitions in model and biological membranes as studied by infrared spectroscopy.

    Source

    Institute of Molecular Science, National Research Council of Canada, Ottawa, Ontario.

    Abstract

    Fourier transform infrared (FT-IR) spectroscopy is an extremely powerful yet non-perturbing physical technique for monitoring the conformation and dynamics of all portions of the phospholipid molecule. In this brief review we summarize some recent FT-IR spectroscopic studies of phospholipid phase transitions in model lipid bilayer and in biological membranes which illustrate the great utility of this technique. We show that FT-IR spectroscopy can accurately monitor the gel to liquid-crystalline phase transition and can provide a large amount of detailed information about phospholipid structure and organization in both the gel and liquid-crystalline states of lipid bilayers.

    PMID:
    2054905
    [PubMed - indexed for MEDLINE]

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