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    Arthritis Res Ther. 2010;12(2):110. Epub 2010 Mar 18.

    Vasculogenesis in rheumatoid arthritis.

    Szekanecz Z, Koch AE.

    Abstract

    Decreased number and impaired functions of endothelial progenitor cells (EPCs) leading to impaired vasculogenesis have been associated with rheumatoid arthritis (RA). Defective vasculogenesis has also been implicated in premature atherosclerosis in RA. Recently, early-outgrowth monocytic and late-outgrowth hemangioblastic EPC subsets have been characterized. Hemangioblastic EPCs may exert increased numbers in active RA and may play a role in vascular repair underlying RA.

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    PMID:
    20346090
    [PubMed - indexed for MEDLINE]
    PMCID: PMC2888181
    Free PMC Article

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