Genome Biol. 2010 Jan 20;11(1):R6.

PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes.

Ruepp A, Kowarsch A, Schmidl D, Buggenthin F, Brauner B, Dunger I, Fobo G, Frishman G, Montrone C, Theis FJ.

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Institute for Bioinformatics and Systems Biology (MIPS), Helmholtz Center Munich - German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany. andreas.ruepp@helmholtz-muenchen.de

Abstract

In recent years, microRNAs have been shown to play important roles in physiological as well as malignant processes. The PhenomiR database http://mips.helmholtz-muenchen.de/phenomir provides data from 542 studies that investigate deregulation of microRNA expression in diseases and biological processes as a systematic, manually curated resource. Using the PhenomiR dataset, we could demonstrate that, depending on disease type, independent information from cell culture studies contrasts with conclusions drawn from patient studies.

PMID:: 20089154; [PubMed - indexed for MEDLINE]
PMCID:: PMC2847718

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