Postgrad Med. 1991 Apr;89(5):175-8, 180.

Neuroleptic malignant syndrome. When levodopa withdrawal is the cause.

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Department of Medicine, Good Samaritan Hospital, Phoenix, AZ 85006.

Abstract

Neuroleptic malignant syndrome has been described in patients receiving dopamine antagonists and in a few patients after withdrawal of dopaminergic antiparkinson therapy. Complications affect almost all organ systems and can be life-threatening. Most patients have fever, altered level of consciousness, bradykinesia, and rigidity. Treatment includes withdrawal of the causative agent and supportive therapy for complications. When withdrawal of a dopaminergic medication is the suspected cause, the agent should be reinstated.

PMID:: 2008397; [PubMed - indexed for MEDLINE]

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