Ann Rheum Dis. 1977 Oct;36(5):399-406.

Chemical composition and swelling of normal and osteoarthrotic femoral head cartilage. II. Swelling.

Abstract

Studies of the equilibrium, partition, and diffusion of tritiated water were carried out on normal and osteoarthrotic cartilage as well as on cartilage from which proteoglycans had been extracted chemically. All the water was found to be freely exchangeable in both normal and degenerate specimens. The diffusiviity of the water was equal to about 40% of the value in free solution, with an activation energy equal to that in free solution. It was concluded that the swelling of degenerate tissue is not due to any changes in the state of the water, but to a failure of the damaged collagen network to oppose the swelling pressure of the proteoglycans. Swelling similar to that observed in fibrillated cartilage was also found in initially normal specimens treated with collagenase.

PMID:: 200188; [PubMed - indexed for MEDLINE]
PMCID:: PMC1000130

Free PMC Article

Publication Types, MeSH Terms, Substances

Publication Types

In Vitro

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Libraries

LinkOut Holdings

Supplemental Content

Save items

Related citations in PubMed

Chemical composition and swelling of normal and osteoarthrotic femoral head cartilage. I. Chemical composition. [Ann Rheum Dis. 1977]
Chemical composition and swelling of normal and osteoarthrotic femoral head cartilage. I. Chemical composition.
Venn M, Maroudas A. Ann Rheum Dis. 1977 Apr; 36(2):121-9.
Biochemical changes in progressive osteoarthrosis. [Ann Rheum Dis. 1977]
Biochemical changes in progressive osteoarthrosis.
Sweet MB, Thonar EJ, Immelman AR, Solomon L. Ann Rheum Dis. 1977 Oct; 36(5):387-98.
Metabolism of human femoral head cartilage in osteoarthrosis and subcapital fracture. [Ann Rheum Dis. 1981]
Metabolism of human femoral head cartilage in osteoarthrosis and subcapital fracture.
Mitrovic D, Gruson M, Demignon J, Mercier P, Aprile F, De Seze S. Ann Rheum Dis. 1981 Feb; 40(1):18-26.
Review Structure and function of proteoglycans of cartilage and cell-matrix interactions. [Soc Gen Physiol Ser. 1977]
Review Structure and function of proteoglycans of cartilage and cell-matrix interactions.
Muir H. Soc Gen Physiol Ser. 1977; 32:87-99.
Review [Histometrical and biochemical study of osteoarthrotic cartilage (author's transl)]. [Acta Rhumatol Belg. 1977]
Review [Histometrical and biochemical study of osteoarthrotic cartilage (author's transl)].
Vignon G, Vignon E. Acta Rhumatol Belg. 1977 Jan-Jun; 1(1-2):9-22.

See reviews... See all...

Cited by 31 PubMed Central articles

Delayed gadolinium-enhanced magnetic resonance imaging of hip joint cartilage: pearls and pitfalls. [Orthop Rev (Pavia). 2011]
Delayed gadolinium-enhanced magnetic resonance imaging of hip joint cartilage: pearls and pitfalls.
Bittersohl B, Zilkens C, Kim YJ, Werlen S, Siebenrock KA, Mamisch TC, Hosalkar HS. Orthop Rev (Pavia). 2011; 3(2):e11. Epub 2011 Jun 29.
Review MR imaging of articular cartilage physiology. [Magn Reson Imaging Clin N Am. ...]
Review MR imaging of articular cartilage physiology.
Choi JA, Gold GE. Magn Reson Imaging Clin N Am. 2011 May; 19(2):249-82.
Changes in Proton Dynamics in Articular Cartilage Caused by Phosphate Salts and Fixation Solutions. [Cartilage. 2010]
Changes in Proton Dynamics in Articular Cartilage Caused by Phosphate Salts and Fixation Solutions.
Zheng S, Xia Y. Cartilage. 2010 Jan 1; 1(1):55-64.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Chemical composition and swelling of normal and osteoarthrotic femoral head cart...
Chemical composition and swelling of normal and osteoarthrotic femoral head cartilage. II. Swelling.
Ann Rheum Dis. 1977 Oct ;36(5):399-406.

PubMed
Interleukin-23 is critical for full-blown expression of a non-autoimmune destruc...
Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORgammat in gammadelta T cells.
Arthritis Res Ther. 2009 ;11(6):R194. Epub 2009 Dec 17 .

PubMed
Proteoglycans as modulators of growth factor activities.
Proteoglycans as modulators of growth factor activities.
Cell. 1991 Mar 8 ;64(5):867-9.

PubMed
Immunoglobulin G galactosylation and sialylation are associated with pregnancy-i...
Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study.
Arthritis Res Ther. 2009 ;11(6):R193. Epub 2009 Dec 16 .

PubMed
Assignment of disulphide bonds in human platelet GPIIIa. A disulphide pattern fo...
Assignment of disulphide bonds in human platelet GPIIIa. A disulphide pattern for the beta-subunits of the integrin family.
Biochem J. 1991 Feb 15 ;274 ( Pt 1):63-71.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: