Cardiol Rev. 2010 Jan-Feb;18(1):20-8.

Assessment of vascular endothelial function with peripheral arterial tonometry: information at your fingertips?

Patvardhan EA, Heffernan KS, Ruan JM, Soffler MI, Karas RH, Kuvin JT.

Source

Vascular Function Study Group, Department of Medicine, Division of Cardiology, Tufts Medical Center, Boston, MA 02111, USA.

Abstract

Endothelial dysfunction is an important component in the pathogenesis of atherosclerosis. The ability to assess the endothelium in a meaningful manner has been the subject of intense investigation over decades. Since the function of endothelial cells is a gauge of vascular health, assessment of vascular function is emerging as a useful tool for predicting cardiovascular risk and as a surrogate outcome measure for cardiovascular reduction intervention studies. This review highlights techniques for assessing endothelial function, focusing on a novel method of determining peripheral vascular reactivity via arterial tonometry.

PMID:: 20010335; [PubMed - indexed for MEDLINE]

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