Am J Hematol. 1991 Mar;36(3):219-20.

Cyclosporine for the treatment of granulocytopenia in Felty's syndrome.

Canvin JM, Dalal BI, Baragar F, Johnston JB.

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Department of Internal Medicine, University of Manitoba, Winnipeg, Canada.

Abstract

A patient with Felty's syndrome was treated with cyclosporine, initially 10 mg/kg/day and then 4 mg/kg/day. The neutrophil count increased by 6 weeks and was normal at 3 months. Over the subsequent 27 months the neutrophil count was closely related to the cyclosporine dosage and there was no evidence of cyclosporine toxicity. This case indicates that cyclosporine may have a role in the treatment of Felty's syndrome.

PMID:: 1996561; [PubMed - indexed for MEDLINE]

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