J Biol. 2009;8(10):91.

Life and death as a T lymphocyte: from immune protection to HIV pathogenesis.

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Lymphocyte Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. vnienke@niaid.nih.gov

Abstract

Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model with its activated CD4(+) T cells are deleted has relevance for HIV infection.

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J Biol. 2009;8(10):93.

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PMCID: PMC2790836

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Life and death as a T lymphocyte: from immune protection to HIV pathogenesis.

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