Crit Care. 2009;13(4):179. Epub 2009 Aug 14.

Challenging the rationale of routine vasopressor therapy for management of hypotension.

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Weil Institute of Critical Care Medicine, Rancho Mirage, CA 92270, USA. weilm@weiliccm.org

Abstract

There is persuasive evidence, including the present report by Dubin and colleagues, of a dissociation between increases in arterial pressure produced by vasopressor agents and improvement in microvascular perfusion and delivery of vital substrates. Especially in settings of septic shock, the current routine administration of adrenergic vasopressor therapy therefore may fail to reverse the primary defect.

Comment on

Crit Care. 2009;13(3):R92.

PMID:: 19691820; [PubMed - indexed for MEDLINE]
PMCID: PMC2750173

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Vasoconstrictor Agents

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Challenging the rationale of routine vasopressor therapy for management of hypotension.

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