Lancet. 1990 Mar 24;335(8691):704-7.

Selective decontamination to reduce gram-negative colonisation and infections after oesophageal resection.

Tetteroo GW, Wagenvoort JH, Castelein A, Tilanus HW, Ince C, Bruining HA.

Source

Department of Surgery, University Hospital Dijkzigt, Erasmus University, Rotterdam, The Netherlands.

Abstract

181 patients undergoing resection of the oesophagus for carcinoma were randomised to receive selective decontamination (test group) or conventional perioperative antibiotic prophylaxis (controls). 114 patients were finally included in the study: 12 of 56 test patients had 18 infections, whereas 32 of 58 controls acquired 51 infections. Colonisation with aerobic gram-negative microorganisms, and the number of postoperative respiratory tract infections were significantly lower in the test patients. The postoperative therapeutic use of antibiotics was significantly lower in the test group. No endogenous infections were caused by gram-negative bacilli in the test group. Selective decontamination reduces colonisation with gram-negative bacilli and postoperative infections after resection of the oesophagus.

PMID:: 1969068; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

Effects of selective decontamination on gram-negative colonisation, infections and development of bacterial resistance in esophageal resection. [Intensive Care Med. 1990]
Effects of selective decontamination on gram-negative colonisation, infections and development of bacterial resistance in esophageal resection.
Tetteroo GW, Wagenvoort JH, Ince C, Bruining HA. Intensive Care Med. 1990; 16 Suppl 3:S224-8.
Randomized, controlled trial of selective digestive decontamination in 600 mechanically ventilated patients in a multidisciplinary intensive care unit. [Crit Care Med. 1997]
Randomized, controlled trial of selective digestive decontamination in 600 mechanically ventilated patients in a multidisciplinary intensive care unit.
Verwaest C, Verhaegen J, Ferdinande P, Schetz M, Van den Berghe G, Verbist L, Lauwers P. Crit Care Med. 1997 Jan; 25(1):63-71.
Review Triple regimen of selective decontamination of the digestive tract, systemic cefotaxime, and microbiological surveillance for prevention of acquired infection in intensive care. [Lancet. 1988]
Review Triple regimen of selective decontamination of the digestive tract, systemic cefotaxime, and microbiological surveillance for prevention of acquired infection in intensive care.
Ledingham IM, Alcock SR, Eastaway AT, McDonald JC, McKay IC, Ramsay G. Lancet. 1988 Apr 9; 1(8589):785-90.
The role of intestinal colonization with gram-negative bacteria as a source for intensive care unit-acquired bacteremia. [Crit Care Med. 2011]
The role of intestinal colonization with gram-negative bacteria as a source for intensive care unit-acquired bacteremia.
Oostdijk EA, de Smet AM, Kesecioglu J, Bonten MJ, Dutch SOD-SDD Trialists Group. Crit Care Med. 2011 May; 39(5):961-6.
Review Role of selective decontamination in surgery. [Br J Surg. 1992]
Review Role of selective decontamination in surgery.
Tetteroo GW, Wagenvoort JH, Bruining HA. Br J Surg. 1992 Apr; 79(4):300-4.

See reviews... See all...

Cited by 10 PubMed Central articles

Selective decontamination of the gastrointestinal tract in patients undergoing esophageal resection. [BMC Surg. 2010]
Selective decontamination of the gastrointestinal tract in patients undergoing esophageal resection.
Näf F, Warschkow R, Kolb W, Zünd M, Lange J, Steffen T. BMC Surg. 2010 Dec 16; 10:36. Epub 2010 Dec 16.
Review Single-drug therapy or selective decontamination of the digestive tract as antifungal prophylaxis in critically ill patients: a systematic review. [Crit Care. 2007]
Review Single-drug therapy or selective decontamination of the digestive tract as antifungal prophylaxis in critically ill patients: a systematic review.
van Till JO, van Ruler O, Lamme B, Weber RJ, Reitsma JB, Boermeester MA. Crit Care. 2007; 11(6):R126.
Effectiveness of antibiotic prophylaxis in critically ill adult patients: systematic review of randomised controlled trials. [BMJ. 1998]
Effectiveness of antibiotic prophylaxis in critically ill adult patients: systematic review of randomised controlled trials.
D'Amico R, Pifferi S, Leonetti C, Torri V, Tinazzi A, Liberati A. BMJ. 1998 Apr 25; 316(7140):1275-85.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Selective decontamination to reduce gram-negative colonisation and infections af...
Selective decontamination to reduce gram-negative colonisation and infections after oesophageal resection.
Lancet. 1990 Mar 24 ;335(8691):704-7.

PubMed
Regional dissemination of KPC-producing Klebsiella pneumoniae.
Regional dissemination of KPC-producing Klebsiella pneumoniae.
Antimicrob Agents Chemother. 2009 Oct ;53(10):4511-3. Epub 2009 Aug 17 .

PubMed
Randomisation and baseline comparisons in clinical trials.
Randomisation and baseline comparisons in clinical trials.
Lancet. 1990 Jan 20 ;335(8682):149-53.

PubMed
In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses...
In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses.
Nature. 2009 Aug 20 ;460(7258):1021-5.

PubMed
The effect of heparin and other glycosaminoglycans on levels of tissue plasminog...
The effect of heparin and other glycosaminoglycans on levels of tissue plasminogen activator and plasminogen activator inhibitor in cultured human umbilical vein endothelial cells.
Blood Coagul Fibrinolysis. 1990 Jun ;1(2):133-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Selective decontamination to reduce gram-negative colonisation and infections after oesophageal resection.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Molecular Biology Databases

Libraries

Supplemental Content

Save items

Related citations in PubMed

Cited by 10 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information